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Head to head

PlushCare vs Sprout Health

A virtual primary-care route to brand-name GLP-1s against a quiz-first compounded service that names its pharmacies.

Short answer

With coverage, PlushCare prescribes a brand-name GLP-1 through your plan for $19.99 a month plus copays. Without coverage, PlushCare estimates about $1,000 a month for the drug, while Sprout Health sells compounded semaglutide at $149 every four weeks, or tirzepatide at $199. Sprout has an FDA warning letter on record (715879).

By Julian RothResearch & dataUpdated October 2026

Disclosure: Aminoscope is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

Is PlushCare or Sprout Health better?

Coverage against disclosure is the trade. PlushCare gives you a primary-care physician by video and an FDA-approved drug at your own pharmacy, with prior authorizations handled. Sprout gives you a flat compounded price, its clinician network and both pharmacies named, and refunds for unshipped months if you cancel a prepaid plan; it serves 44 states and keeps a $50 fee if you cancel after review. PlushCare's membership is $19.99 a month after a free first month, with each visit $129 without insurance. Sprout received FDA warning letter 715879 in September 2025, linked below.

How they differ

Published up front

PlushCare

$19.99/mo membership plus $129 per visit without insurance (a copay with it) — medication billed separately

Sprout Health

Semaglutide $149 and tirzepatide $199 every 4 weeks month-to-month; $99 and $149/mo on a prepaid 12-month plan
Insurance

PlushCare

Works with insurance

Sprout Health

Cash-pay only
How you're seen

PlushCare

Video visit

Sprout Health

Quiz intake / Async intake / Video visit
Medications

PlushCare

Branded medication

Sprout Health

Compounded semaglutide, Compounded tirzepatide
Availability

PlushCare

All 50 states + D.C.

Sprout Health

44 states
FDA warning letter

PlushCare

None on record

What each one costs and includes

Month-to-month prices a new patient can buy, with any required membership counted in. First-month promotions and prepaid averages are labeled as such.

First full month

PlushCare

$19.99 a month (first month free) plus $129 a visit without insurance, or your copay; the drug is billed by your pharmacy

Sprout Health

$149 every four weeks for compounded semaglutide, or $199 for tirzepatide
Once you're on a steady dose

PlushCare

Depends on drug coverage; without it, branded weight-loss drugs run about $1,000 a month by PlushCare's own estimate

Sprout Health

The same four-weekly price (13 charges a year); a 12-month prepay cuts it to $99 or $149 a month
What the fee covers

PlushCare

Messaging, same-day appointments and lab discounts; visits are billed separately

Sprout Health

Medication and clinician review through MD Integrations, with a refill questionnaire before each shipment
Medications

PlushCare

Brand-name: Wegovy, Zepbound, Saxenda and Contrave for weight, sent to the pharmacy you choose

Sprout Health

Compounded only: semaglutide and tirzepatide from Foothills Pharmacy and Promise Pharmacy
Insurance

PlushCare

In network with most major insurers for visits, and handles prior authorizations for the drug

Sprout Health

Cash-pay
Commitment and refunds

PlushCare

Cancel anytime; the membership fee is never refunded

Sprout Health

Cancel 48 hours before billing; a $50 review fee is kept if you cancel after a provider has reviewed you; not available in six states
How care works

PlushCare

A board-certified primary-care physician by video, often the same day; usually two visits and labs before a prescription

Sprout Health

A quiz-first intake, a detailed medical questionnaire after you pay, and a refill questionnaire before every shipment
Look elsewhere if

PlushCare

You're paying cash for the drug, want compounded medication or want a coached weight program

Sprout Health

You live in an unserved state, want brand-name medication, or don't want a questionnaire before every refill

PlushCare

Access
$19.99/mo membership plus $129 per visit without insurance (a copay with it) — medication billed separately
Medications
Branded
Insurance
Works with insurance
Visit
Video visit

What we like

  • Board-certified primary-care physicians by video, often the same day, in all 50 states and D.C.
  • In-network with most major insurers for visits, and prior authorizations are handled for you
  • Brand-name medication sent to the pharmacy you choose

Watch-outs

  • Medication and labs are billed separately from the membership and visits
  • Without coverage, branded drugs cost about $1,000 a month by PlushCare's own estimate

Pick PlushCare if: You want a brand-name drug billed through insurance.

Check PlushCare availability →Read the full PlushCare review →

Sprout Health

Access
Semaglutide $149 and tirzepatide $199 every 4 weeks month-to-month; $99 and $149/mo on a prepaid 12-month plan
Medications
Semaglutide · Tirzepatide
Insurance
Cash-pay
Visit
Quiz intake / Async intake / Video visit

What we like

  • Names its clinician network and both dispensing pharmacies in its terms
  • A clear month-to-month price, with a 12-month plan that cuts semaglutide to $99 a month
  • Refunds for unshipped months if you cancel a prepaid plan early

Watch-outs

  • Monthly plans bill every four weeks, so you pay 13 times a year
  • Not available in Alabama, Arkansas, California, Louisiana, Mississippi or North Dakota

Pick Sprout Health if: You're paying cash and want the compounding pharmacy named.

Check Sprout Health availability →Read the full Sprout Health review →

Want the full field? See every option in our GLP-1 providers roundup, or narrow by tirzepatide / semaglutide and price.