Cielo review

What it is

Cielo Health is a telehealth platform based at 7901 4th Street North in St. Petersburg, Florida. Its privacy policy describes it as a technology and administrative company, not a medical provider, and its terms say it is contracted with MD Integrations, a clinician network used by a number of telehealth brands. The independent clinicians in that network make the treatment decisions. Cielo sells only two products, compounded semaglutide and compounded tirzepatide, with no brand-name drugs and no other treatment lines. Its site is available in English and Spanish, customer service runs from 9 a.m. to 8 p.m. Eastern every day by phone, email or chat, and the company says it donates 10% of every dollar it earns to charities focused on faith, recovery and basic needs. Users must be 18 or older, and its terms are governed by Florida law.

How it works

You start with a secure online health intake. A licensed provider reviews it, usually the same day, and if you meet the clinical criteria you can be approved without a live telehealth appointment. Once payment is processed and the prescription is approved, the medication ships, and it usually arrives within two to three business days. From there, the plan includes unlimited provider access, follow-up care and help with refills, and the company says same-day appointments are available if you want to talk to someone. Dosing is personalized, with your provider adjusting it over time. Cielo describes its formulations as including additives meant to help retain muscle, boost energy and reduce nausea, but it doesn't say what those additives are, so ask before you order.

Pricing transparency

Each medication has three plan lengths, and the price doesn't change with your dose. Compounded semaglutide is $89 a month on the six-month plan, $99 a month on the three-month plan and $139 a month on the monthly plan. Compounded tirzepatide is $129, $149 and $189 a month on the same plans. Those monthly prices appear under a flash-sale banner, next to regular prices of $199 for semaglutide and $299 for tirzepatide, so the month-to-month figure could rise when the sale ends. Over six months, semaglutide costs $534 on the six-month plan, $834 on the monthly plan at the sale price and $1,194 at the regular price, so the commitment matters. Free expedited shipping is included, along with the provider review and ongoing care. The company says there are no contracts and you can cancel any time, and that you're only responsible for medication that has already shipped. It doesn't publish a fuller refund policy or explain how the multi-month plans are billed, so check at checkout whether a six-month plan is charged up front or monthly. Insurance isn't accepted.

Branded vs compounded

Cielo prescribes compounded semaglutide and compounded tirzepatide as weekly injections. It says its medication is compounded in the United States by regulated pharmacy partners, and that every batch is tested, but it doesn't name the pharmacy or post test results. Compounded medications are not FDA-approved. Brand-name Wegovy, Ozempic, Zepbound and Mounjaro aren't offered, and neither is an oral option. The "lose up to" figures on its product cards, 21% for semaglutide and 27% for tirzepatide, are upper-end numbers rather than averages, and the site doesn't say which studies they come from. A search of the FDA warning-letter database under Cielo Health and its web address returned no letters, and the site doesn't display a LegitScript seal.

Pros and watch-outs

The evidence behind what Cielo prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• What the semaglutide weight-loss trials actually showed

  STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.

• Tirzepatide vs semaglutide for weight loss: what the trials actually support

  Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.

• Compounded vs branded GLP-1: regulatory status, sourcing and the evidence

  Compounded GLP-1 isn't FDA-approved, the shortage exception behind it ended in 2025, the FDA moved against mass-marketed copies in 2026, and the trial data belong to the branded product. Here's the precise picture.

How Cielo compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Collective

  A low all-in GLP-1 cost, if you will actually keep the annual membership

  See Collective →
• MEMEDGm

  Readers who want compounded and brand-name GLP-1 routes presented side by side

  See MEDGm →
• Actin

  Cash buyers who want a flat price at every dose, no membership and the option to cut the monthly cost with a longer plan

  See Actin →

More GLP-1 telehealth reviews: Nova · Oria Meds · RENN Health · SexyMD · Solaya MD · VevaRX