Dr. Gillis' Wellness Center review

What it is

Dr. Gillis' Wellness Center is a clinic in Oakland, Maine, founded in 2023 and led by Dr. Gillis, a board-certified physician and surgeon with more than 25 years in gut health and gastrointestinal surgery who serves on the Maine State Medical Board. It runs nationwide telehealth, with a named peptide menu covering sermorelin, CJC-1295/ipamorelin, tesamorelin, GHK-Cu, glutathione and NAD⁺, alongside GLP-1 weight-loss care in both injectable and sublingual orally dissolving tablet form. Its GLP-1 line runs semaglutide, tirzepatide and retatrutide with no contracts.

How it works

A small clinic operating telehealth, with a real physician's name attached to it — and unusually, a physician whose credentials are checkable and whose specialism is a real one rather than a wellness qualification. Scheduling is flexible on a weekly, bi-weekly or monthly cadence with no contracts, which is a patient-friendly structure and the opposite of the six- and twelve-month prepay lock-ins common elsewhere. The needle-free sublingual ODT option on the GLP-1 side is a genuine differentiator for needle-averse patients, though it does not extend to the peptide line. What the clinic does not publish is a state list behind its nationwide telehealth claim, any pricing for the peptide menu, or a named compounding pharmacy. There is no lab work described in the default path either, which is worth pausing on given that four of the six named peptides act on or around the growth-hormone axis — an IGF-1 baseline is the obvious thing to want before starting one, and here you would need to arrange it yourself or ask for it explicitly.

Pricing transparency

Published for GLP-1 and published nowhere for peptides. On the weight-loss side, the clinic lists a $150 starting dose of semaglutide, monthly treatment plans from $149, and oral GLP-1 therapies from $149, with no contracts. Those are entry prices rather than a per-dose schedule, so what a maintenance dose costs is not visible in advance even on the GLP-1 line. For sermorelin, CJC-1295/ipamorelin, tesamorelin, GHK-Cu, glutathione and NAD⁺, no price appears anywhere and the site directs you to contact the office — so we are not quoting one, and the $149 figure is a GLP-1 price that says nothing about any of them. Ask for the monthly cost of the specific peptide you want, what dose and quantity it supplies, whether the price changes as the dose escalates, and whether the no-contract flexibility applies to the peptide line the way it does to GLP-1 plans.

Branded vs compounded

Compounded; not FDA-approved. Prescription required only if a licensed provider finds it appropriate. The clinic does not name its compounding pharmacy, and compounded sterile products are not FDA-reviewed for purity and potency the way approved drugs are. The value of naming six peptides is that we can actually assess them — and they do not sit at the same level, which is the thing the site does not tell you. Sermorelin, CJC-1295/ipamorelin and tesamorelin all act on the growth-hormone axis, a real and well-described mechanism; tesamorelin is the outlier with genuine FDA-approved human evidence, but for HIV-associated lipodystrophy specifically rather than general wellness, and the compounded versions sold here are not the approved product. For sermorelin and CJC-1295/ipamorelin the long-term human outcome data stays thin and no controlled trial supports the body-composition or anti-aging claims the category runs on. GHK-Cu and injectable glutathione are lower again, with essentially no controlled human outcome evidence for the skin, recovery and wellness claims attached to them. NAD⁺ by injection has no controlled outcome trials; the oral precursors NR and NMN are the forms with human data, and they raise blood NAD⁺ rather than demonstrating a clinical benefit. On the GLP-1 side, retatrutide is an investigational molecule not approved anywhere, and the compounded status of the sublingual products is not explicitly stated on the site. Individual results vary.

Pros and watch-outs

The evidence behind what Dr. Gillis' Wellness Center prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• Sermorelin: a real GHRH drug, read against the anti-aging pitch

  An approved growth-hormone-releasing analog with a pediatric track record — and a longevity case built more on biomarkers than outcomes.

• NAD+ precursors (NR and NMN): what the human trials actually show

  They raise NAD+ and look safe short-term — but human evidence is surrogate-marker level, and no trial shows they extend healthspan.

• Glutathione: the master antioxidant, and where the evidence actually is

  Oral glutathione really does raise your body stores (a 6-month RCT proved it) — but the longevity and detox claims are unproven, skin-lightening is modest, and IV glutathione is the most marketed, least evidenced route. The precursors may be the smarter bet.

• Ipamorelin & CJC-1295: the honest evidence on GH secretagogue peptides

  They reliably raise growth hormone — that part is real. The muscle, fat-loss and anti-aging claims are not supported by human outcome data. A straight read.

• Tesamorelin (Egrifta): what it's actually FDA-approved for, and the evidence

  A real, approved GHRH analog — for HIV-associated lipodystrophy specifically. What the pivotal trials showed, and why the longevity use is an extrapolation.

• GHK-Cu: the copper peptide between real skincare and overclaim

  A decades-deep molecule with a credible topical story — and systemic anti-aging claims that outrun the human data.

How Dr. Gillis' Wellness Center compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Live Vital

  Pairing a GLP-1 with a wider peptide and longevity protocol

  See Live Vital →
• RxSpan MD

  Branded and compounded GLP-1 under named physician oversight

  See RxSpan MD →
• Invigor Medical

  Prescription at-home NAD⁺ injections via telehealth

  See Invigor Medical →