One80Rx review
By Aminoscope editorial desk · Aminoscope
Clarify cancellation first
Our verdict
One80Rx lists compounded GLP-1 injections, NAD+ and selected peptides. Its terms describe a bundled monthly subscription, while the treatment FAQs and legal terms give different cancellation notice periods.
Main trade-offs
- 48-hour versus 30-day cancellation conflict
- Selected supply, pharmacy and lab fees unknown
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Compounded medicines are not FDA-approved. A licensed clinician must assess whether treatment is appropriate; availability does not establish safety or benefit.
Good fit
Self-pay adults who can obtain a written treatment quote and resolve the cancellation deadline before subscribing.
Consider other options if
Readers who need a confirmed first charge, a named pharmacy or an unambiguous cancellation deadline from public pages alone.
Cost and care at a glance
- Category
- GLP-1 telehealth
- Published cost
- Advertised starting rates: semaglutide injection $129/month; tirzepatide injection $229. Selected dose, first charge and supply unconfirmed
- Medications
- Compounded semaglutide injection · Compounded tirzepatide injection
- Insurance
- Cash-pay, no insurance
- Availability
- Operating-state eligibility applies; no product-specific state list established
Our review in detail
Full assessment
Get the selected prescription price, supply and cancellation cutoff in writing before paying. The advertised starting rates do not establish a specific dose or first charge, and the conflicting deadlines could affect your next renewal.
What it is
One80Rx LLC is a platform connecting patients with independent clinicians and pharmacies. It does not itself practice medicine or dispense prescriptions. The public pages do not identify the medical group and dispensing pharmacy assigned to a particular patient.
How care works
The service is for adults aged 18 or older, or the higher local age of majority, physically located in a state where it operates. Treatment depends on clinician review. The home page describes nationwide telehealth, but a product-specific state list is not established.
One80Rx advertises no insurance requirement, no consultation or dose-change surcharge, free two-to-three-day shipping and no charge if a provider does not approve. The terms also allow disclosed taxes and shipping charges, so confirm the selected order total. No guaranteed review-to-delivery time or medication supply is established. Peptide pages discuss clinical monitoring and, for tesamorelin, baseline labs; lab inclusion and fees are not specified.
Costs, billing and cancellation
The current catalog advertises semaglutide injection from $129/month, tirzepatide injection from $229, GLP-1 microdose from $149 and a generic oral GLP-1 option from $149. It also lists NAD+ from $159, sermorelin from $210, tesamorelin from $239 and PT-141 from $210. These are advertised starting rates, not verified selected-dose prices, supply quantities or first debits. The oral option does not identify a molecule, so its headline cannot establish an oral semaglutide or tirzepatide price.
The terms describe an immediate charge and renewal every 30 days for monthly subscriptions, with a reminder five to seven days before a transaction. One bundled price covers the pharmacy, medical-group service and platform.
Cancellation is the main concern: the terms say turn off auto-refill at least 48 hours before monthly processing, while semaglutide, tirzepatide and microdose FAQs require 30 days’ notice before the next bill. Neither should be treated as an unconditional cancel-anytime promise. Ask which rule governs your plan.
An initial prescription order may be canceled within 24 hours only if the provider network has not received it. Dispensed or delivered medication is generally nonrefundable. The terms list exceptions for wrong, damaged, unsafe or unshipped products and provider-declined prescriptions. Wrong or damaged items should be reported within 48 hours; a returned prescription may incur a $35 disposal fee.
Medication and evidence
Current public pages identify compounded semaglutide and tirzepatide injections, sermorelin, tesamorelin and PT-141. The microdose and oral GLP-1 listings do not establish a molecule. NAD+ is clinician-reviewed, with route and schedule selected by the provider; the description does not establish a fixed injection or IV package.
Compounded medicines are not FDA-approved, and advertising a program does not establish its clinical benefit or suitability.
Sources checked
Pros and watch-outs
What we like
- Subscription components described in the terms
- Current catalog distinguishes several treatment options
- Provider-decline refunds addressed publicly
Watch-outs
- 48-hour versus 30-day cancellation conflict
- Selected supply, pharmacy and lab fees unknown
- Oral GLP-1 molecule not identified
Best for
Self-pay adults who can obtain a written treatment quote and resolve the cancellation deadline before subscribing.
Who should look elsewhere
Readers who need a confirmed first charge, a named pharmacy or an unambiguous cancellation deadline from public pages alone.
Research relevant to One80Rx
Explore the evidence and its limits. Findings apply to the formulation, route and population studied; they do not establish the quality or effectiveness of a provider’s products.
- What the semaglutide weight-loss trials actually showed
STEP 1, STEP 4 and SELECT, plus oral and higher-dose semaglutide trials: weight loss, withdrawal, cardiovascular benefit and the limits of comparison.
- Tirzepatide vs semaglutide for weight loss: what the trials actually support
SURMOUNT-5 found 20.2% versus 13.7% average weight loss. What that direct comparison supports, which doses it tested, and why newer formulations need separate evidence.
- Sermorelin benefits: does it work? What the trials show
A real GHRH drug, read against the anti-aging pitch: an approved growth-hormone-releasing analog with a pediatric track record, and a longevity case built more on biomarkers than outcomes.
How One80Rx compares
A few alternatives worth a look, depending on what you’re optimizing for.
SnagRxNaming the pharmacies that actually fill the prescription
See SnagRx →- HumeCare+
Someone who wants a device-based program and will confirm the complete quote and eligibility.
See HumeCare+ → 
SkinnyRxAdults comparing compounded treatment who obtain a written renewal quote and cancellation deadline
See SkinnyRx →
More GLP-1 telehealth reviews: ReflexMDTeleios HealthTideMedixRilaSipraMeli Health
Editorial research
How we assessed this. This review reflects Aminoscope’s own read of One80Rx’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How much does One80Rx semaglutide cost?
- The catalog advertises injections from $129/month. It does not establish your selected dose, supply, initial charge or renewal total.
- Does One80Rx require 48 hours or 30 days to cancel?
- The terms use a 48-hour cutoff before monthly processing, while treatment FAQs say 30 days before billing. Obtain written confirmation for your plan before paying.
- Does One80Rx identify its oral GLP-1 medication?
- The public catalog lists an oral GLP-1 option but does not identify the molecule. Its eligibility link does not establish an oral semaglutide or tirzepatide formulation.
- Are NAD+ injections guaranteed to be available?
- The public page leaves route and schedule to the provider. It does not establish a fixed injection or IV treatment package.
- Is One80Rx legit?
- One80Rx is a GLP-1 telehealth service. The medications it names are Compounded semaglutide injection and Compounded tirzepatide injection. Its stated availability: Operating-state eligibility applies; no product-specific state list established. What it publishes up front: Advertised starting rates: semaglutide injection $129/month; tirzepatide injection $229. Selected dose, first charge and supply unconfirmed. It is cash-pay and states it does not bill insurance. Before you pay, ask in writing about a single monthly price you can check before an intake and how its intake works.