PreventiveMD review

What it is

PreventiveMD (PreventiveMD, Inc.) is a physician-guided telehealth platform selling two lines from one price list. Its GLP-1 and weight-loss line runs compounded semaglutide from $83/mo and compounded tirzepatide from $97/mo, both stated all-in, plus brand Wegovy, Zepbound and Foundayo on a membership model. Its peptide therapy line runs GHK-Cu from $89/mo, glutathione from $94/mo, NAD⁺ from $119/mo and sermorelin from $119/mo, each all-in. Prescribing is through a named participating medical group, LocumTele, LLC, and its terms are governed by Massachusetts law.

How it works

Asynchronous and unusually low-risk at the front door. A US-licensed provider reviews your request within 24 hours with no video visit required, and if approved your medication ships; checkout places an authorisation hold rather than a charge, so you are not billed before a clinician has decided. It states one transparent monthly price with no insurance and no claims, describes its offerings as HSA/FSA eligible with submittable receipts, and — the disclosure that stands out — publishes its state availability in its own homepage FAQ, naming Alaska, Arkansas, the District of Columbia, Idaho, Kansas, Mississippi, New Jersey, New Mexico, New York, Rhode Island, South Dakota, Vermont, Virginia, West Virginia and Wisconsin as places it does not yet serve. On the trust side it displays LegitScript certification along with HIPAA, SSL and accessibility badges, and names its participating medical group. Two gaps remain. Individual compounding pharmacies are never named, only described as state-licensed US 503A facilities — a material transparency gap for a prescription purchase. And the refund policy is strict once things are in motion: you may cancel for a full refund before a provider has reviewed your request and before the pharmacy has placed or shipped the order, but once either has happened the order is non-refundable.

Pricing transparency

The clearest peptide price list in this batch and the cheapest. GHK-Cu is as low as $89 a month, glutathione $94, NAD⁺ $119 and sermorelin $119, each stated as all-in per month. That is a genuine per-molecule figure rather than a category headline, and it is published without an intake. Read "as low as" as written: there is no per-dose price list behind it and no flat-price statement, so your actual cost can be higher depending on what a provider prescribes. Two structural things to note about the rest of the price list, because they show how the same platform prices differently. Compounded semaglutide at $83 and tirzepatide at $97 are also all-in with no separate fee. But the brand medications are not: Wegovy and Foundayo are quoted as a $49 a month membership fee plus medication from $149, and Zepbound as $49 plus medication from $299 — a two-part structure that does not apply to the peptide line. Nothing on the GLP-1 side is a peptide price and none of it should be read as one.

Branded vs compounded

Compounded; not FDA-approved. Prescription required only if a licensed provider finds it appropriate. PreventiveMD states it works exclusively with state-licensed US 503A compounding pharmacies following strict quality standards, but does not name them, and compounded sterile products are not reviewed by the FDA for purity and potency the way approved drugs are. Its terms confirm that the price you pay covers both the pharmacy's charge for the drug and the medical group's charge for the provider's services, which is what "all-in" should mean and is worth checking against competitors who use the phrase loosely. On evidence, the four peptide products sit at very different tiers despite similar prices. Sermorelin is a GHRH analogue that prompts your own pituitary — a real mechanism whose long-term human outcome data stays thin. GHK-Cu is a copper-binding tripeptide with a genuinely interesting cell and animal literature on collagen and wound repair and essentially no controlled human outcome trials behind the skin claims sold on it. Injectable glutathione has essentially none either. Injected NAD⁺ has no controlled human outcome trials; the oral precursors NR and NMN are the studied forms and raise a blood level rather than an outcome. Individual results vary.

Pros and watch-outs

The evidence behind what PreventiveMD prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• GHK-Cu: the copper peptide between real skincare and overclaim

  A decades-deep molecule with a credible topical story — and systemic anti-aging claims that outrun the human data.

• Sermorelin: a real GHRH drug, read against the anti-aging pitch

  An approved growth-hormone-releasing analog with a pediatric track record — and a longevity case built more on biomarkers than outcomes.

• NAD+ precursors (NR and NMN): what the human trials actually show

  They raise NAD+ and look safe short-term — but human evidence is surrogate-marker level, and no trial shows they extend healthspan.

• Glutathione: the master antioxidant, and where the evidence actually is

  Oral glutathione really does raise your body stores (a 6-month RCT proved it) — but the longevity and detox claims are unproven, skin-lightening is modest, and IV glutathione is the most marketed, least evidenced route. The precursors may be the smarter bet.

How PreventiveMD compares

A few alternatives worth a look, depending on what you’re optimizing for.

• PLPlexusDx

  NAD⁺ at a published all-in monthly price with check-ins and no membership on top

  See PlexusDx →
• PAPauseRX

  NAD⁺ buyers who want a named 503A pharmacy and a named prescribing network

  See PauseRX →
• PEPepHaūs

  People who will pin the actual NAD⁺ monthly rate down in writing before intake

  See PepHaūs →