RxION Health review
Flat pricing, candid page
Flat per-molecule pricing that does not climb as your dose does — and an NAD⁺ page that says out loud what the evidence does not support.
Our verdict
RxION publishes a price for every molecule on its anti-aging shelf — sermorelin $299, NAD⁺ $249, glutathione $224 — and holds each one flat at every dose, which removes the most common way a cheap-looking peptide plan gets expensive. It goes further than almost anyone here on one page: its NAD⁺ listing states plainly that compounded NAD⁺ is not FDA-approved for anti-aging, energy, cognitive or longevity indications, printed directly under the buy button. What it will not tell you is where it is, who runs it, or which pharmacy prepares the medication.
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At a glance
- Category
- Peptide telehealth
- Access
- NAD⁺ $249/mo flat at every dose; free overnight cold-pack shipping and supplies, not available in NJ, AK or MS
- Insurance
- Cash-pay, no insurance
- Visit
- Async intake
- Availability
- US except New Jersey, Alaska and Mississippi
- LegitScript
- Certified
- Updated
- July 2026
Popular alternative
Oak Longevity
Low-cost sermorelin within a broader longevity stack
Check Oak Longevity availability →What it is
RxION Health is a LegitScript-certified telehealth platform organised in three bands: weight management (compounded semaglutide and tirzepatide, branded Wegovy and Zepbound, LIPO-B and a microdose GLP-1 program), anti-aging and longevity (sermorelin, NAD⁺ and glutathione, all compounded injectables), and sexual health (PT-141). Every anti-aging product is sold as a monthly supply with the consultation, medication if prescribed, free cold-pack overnight shipping, all injection supplies and instructions, and ongoing clinical support inside a single figure.
How it works
A four-step storefront flow: pick the medication, complete a secure online intake, a licensed provider reviews it and decides whether treatment is appropriate, and if approved the prescription ships from a licensed US pharmacy in temperature-conscious packaging. The site is explicit that no medication is dispensed without provider approval and that not all patients will be eligible, and that the price reflects the consultation plus medication if prescribed — which is honest framing for a pay-first model. Its quality-control disclosure is unusually concrete for this board: batches tested for potency to within ±10% of the labelled concentration every three to six months, pH balance to limit injection-site irritation, sterility to USP <797> standards, and endotoxins held under the USP <85> thresholds. Stating the actual standards rather than saying "lab-tested" is a meaningful difference. Set against that, the identity layer is thin: no physical address, no named medical director or clinical leadership, no operating-entity detail beyond the brand, and partner pharmacies described as licensed and FDA-regulated but never named. Coverage is stated by exclusion — not available to residents of New Jersey, Alaska or Mississippi — rather than as a positive state list. The site also displays an aggregate patient score, which is not a signal we give any weight to and which forms no part of this assessment.
Pricing transparency
Published, flat and per-molecule, which is the reason to look. Sermorelin is $299 a month, NAD⁺ $249 a month and glutathione $224 a month, each stated as the same price at every dose with no surprise increases, and each including the provider consultation, the medication if prescribed, free cold-pack overnight shipping, all supplies and step-by-step injection instructions, and ongoing clinical support. The flat-at-every-dose promise is the substantive part: on a therapy your provider is expected to titrate, a plan priced by dose can double between month one and month six, and this one cannot. Sermorelin at $299 sits at the upper end of this batch, and glutathione at $224 above several peers, so this is transparency rather than value — you are paying a premium for a price that does not move. What is not stated anywhere is dose, concentration or vial size, so a month is undefined in volume terms; ask before subscribing, since that is what separates $299 here from a lower figure elsewhere. Its GLP-1 line is priced separately at $199 a month for semaglutide and $299 for tirzepatide with promotional rates running below both — those are weight-loss numbers and are not a peptide price.
Branded vs compounded
Compounded; not FDA-approved. Prescription required only if a licensed provider finds it appropriate. RxION's NAD⁺ page carries the disclosure this whole category should carry and mostly does not: compounded NAD⁺ is not FDA-approved for anti-aging, energy, cognitive or longevity indications, individual responses vary, and use is at the discretion of a licensed provider after evaluation — printed on the page selling the product rather than in a footer. That is worth more than most trust badges. Compounded sterile products are still not reviewed by the FDA for purity and potency the way approved drugs are, and RxION does not name the pharmacy preparing them. On the evidence, the shelf is not one thing. Sermorelin is a GHRH analogue that prompts your own pituitary to release growth hormone, preserving the somatostatin feedback loop injected HGH overrides — a real, well-characterised mechanism whose long-term human outcome data thins out badly past short-term IGF-1 changes. Injected NAD⁺ has no controlled human outcome trials at all; the single human intravenous study was a pharmacokinetic pilot showing infused NAD⁺ clears from plasma quickly, and the forms with human trial data are the oral precursors NR and NMN, which raise blood NAD⁺ — a biomarker, not an outcome. Injectable glutathione has essentially no controlled human outcome data behind the detoxification, immune and skin claims made for it. PT-141 is the exception in the other direction: the injectable bremelanotide is FDA-approved, but only for generalised hypoactive sexual desire disorder in premenopausal women, so any other use is off-label and a compounded version is not the approved product. Individual results vary.
Pros and watch-outs
What we like
- Sermorelin $299, NAD⁺ $249 and glutathione $224 all published before intake, flat at every dose with no titration increases
- Consultation, medication, free cold-pack overnight shipping, all supplies and ongoing clinical support inside the single figure
- States on the NAD⁺ product page itself that compounded NAD⁺ is not FDA-approved for anti-aging, energy, cognitive or longevity indications
- Publishes concrete testing standards — potency to ±10% every three to six months, pH, sterility to USP <797>, endotoxins to USP <85>
- LegitScript certification displayed, with state exclusions stated openly rather than buried
Watch-outs
- Not available to residents of New Jersey, Alaska or Mississippi
- No physical address, no named medical director and no operating-entity detail beyond the brand
- Partner pharmacies described as licensed and FDA-regulated but never named
- No dose, concentration or vial size published beside any price, so a month is undefined in volume
- Sermorelin at $299 and glutathione at $224 sit at the upper end of this batch's range
Best for
People who want a peptide or NAD⁺ price that will not rise as their provider titrates them up, and who value a candid on-page evidence disclaimer.
Who should look elsewhere
Residents of the three excluded states, price-sensitive sermorelin buyers, or anyone who needs a named pharmacy, address or medical director before starting.
The evidence behind what RxION Health prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- Sermorelin: a real GHRH drug, read against the anti-aging pitch
An approved growth-hormone-releasing analog with a pediatric track record — and a longevity case built more on biomarkers than outcomes.
- NAD+ precursors (NR and NMN): what the human trials actually show
They raise NAD+ and look safe short-term — but human evidence is surrogate-marker level, and no trial shows they extend healthspan.
- Glutathione: the master antioxidant, and where the evidence actually is
Oral glutathione really does raise your body stores (a 6-month RCT proved it) — but the longevity and detox claims are unproven, skin-lightening is modest, and IV glutathione is the most marketed, least evidenced route. The precursors may be the smarter bet.
- PT-141 (bremelanotide): the evidence on a research-popular peptide that is actually FDA-approved
Bremelanotide (Vyleesi) is FDA-approved for HSDD in premenopausal women, with phase-3 trial evidence. A straight read of what's proven — and where off-label use goes beyond it.
How RxION Health compares
A few alternatives worth a look, depending on what you’re optimizing for.
- Revel Health
Comparing injected against intranasal NAD⁺ at two published prices in one place
See Revel Health → - REMEVi
Choosing between injected, nasal and oral NAD⁺ without the price changing
See REMEVi → - Rewinding RX
NAD⁺ buyers who want concentration, vial size and a dosing ladder published with the price
See Rewinding RX →
Pharmacology & mechanisms · Reviewed and last verified July 2026
How we assessed this. This review reflects Aminoscope’s own read of RxION Health’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- What does sermorelin cost at RxION Health?
- $299 a month, published on the product page and stated as the same price at every dose with no surprise increases. That figure includes the provider consultation, the medication if prescribed, free cold-pack overnight shipping, all supplies and injection instructions, and ongoing clinical support. NAD⁺ is $249 and glutathione $224 on the same basis. Compounded; not FDA-approved.
- What does "same price at every dose" actually save me?
- It removes the most common way a peptide plan gets expensive. Sermorelin and NAD⁺ are titrated, and a plan priced by dose can climb substantially between your first month and your sixth. RxION's rate is fixed across the ladder — so it may look expensive against a competitor's entry tier and cheaper against that competitor's maintenance tier.
- Is compounded NAD⁺ approved for energy or anti-aging?
- No, and RxION says so on its own product page: compounded NAD⁺ is not FDA-approved for anti-aging, energy, cognitive or longevity indications. Injected NAD⁺ has no controlled human outcome trials; the NAD⁺ forms with human trial data are the oral precursors NR and NMN, and what those show is a raised blood NAD⁺ level rather than a clinical outcome.
- Where does RxION not operate, and who compounds the medication?
- It is not available to residents of New Jersey, Alaska or Mississippi, stated on every product page. The pharmacies are described only as licensed US partners using FDA-regulated ingredients and are never named, and no physical address or medical director is published. Ask which pharmacy prepares your prescription before your first order.