ZYP Medical review
One provider, hour-long first visit
A one-provider Nebraska practice with a free hour-long consult, compounded semaglutide and tirzepatide with in-between doses, and tirzepatide tablets at $250 a month. Seven states.
Our verdict
ZYP Medical is the opposite of a high-volume telehealth brand: one nurse practitioner, an hour-long free first visit, and direct text access to the same person for as long as you're a patient. It suits people who want to be walked through the medication, dosed slowly and given a plan for after they stop. The pricing is honest but not simple. Injectable starter plans are paid up front ($399 for 10 weeks of semaglutide, $450 for two months of tirzepatide), and later orders are priced by your dose and how much you buy at once, so the monthly cost moves. Tirzepatide tablets are a cleaner $250 for a 30-day supply. Care is limited to seven states, and everything is final sale. For people in those states who have been put off by five-minute intake forms elsewhere, the trade is a good one: more time with a clinician in exchange for less pricing simplicity.
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At a glance
- Category
- GLP-1 telehealth
- Access
- Tirzepatide tablets $250 per 30-day supply; injectable starters prepaid ($399 semaglutide, $450 tirzepatide); refills priced by dose
- Medications
- Compounded semaglutide · Compounded tirzepatide
- Insurance
- Cash-pay, no insurance
- Visit
- Video visit
- Availability
- 7 states (NE, IA, SD, MN, KS, CO, AZ)
Partner alternative
yourEra
A low-cost entry point into compounded GLP-1 treatment
Check yourEra availability →What it is
ZYP Medical, LLC is a direct-pay practice at 11922 Standing Stone Drive in Gretna, Nebraska, just outside Omaha. Its founder and only listed provider is Josh Peterson, a board-certified family nurse practitioner who reports more than 35,000 patient encounters in emergency medicine, urgent care and family medicine before starting ZYP. Besides weight loss, the practice offers testosterone therapy, virtual urgent care at $75 a visit, peptide and NAD⁺ therapy, lab testing, therapeutic phlebotomy and IV hydration. Weight-loss care is available by telehealth to people who live in Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado and Arizona, and in person at the Gretna clinic. ZYP says it doesn't run ads and grows through referrals, offering account credit to patients who send a friend. It doesn't display LegitScript certification.
How it works
Every new plan starts with a free consult: an hour with Josh Peterson by video or in person, covering your history, medications, goals, semaglutide versus tirzepatide, side-effect management and a plan for keeping weight off after the medication. (A lower block of the same page lists a $50 hour-long Deep Dive and a $29.99 30-minute Power Consult for people already experienced with GLP-1s, so ask which applies when you book.) Most patients qualify with a BMI of 30 or more, or 27 or more with a weight-related condition. If treatment is appropriate, the prescription can go out right after the visit and medication usually arrives in three to five business days. ZYP titrates slowly and offers in-between doses, such as 3.5 mg of tirzepatide rather than a jump from 2.5 to 5 mg. You text the provider directly for help, with a check-in before each refill. Some stable patients are moved to dosing every 10 to 14 days to stretch a supply, but only with the provider's approval.
Pricing transparency
The semaglutide starter plan is $399 paid in full for 10 weeks (0.25 mg, then 0.5 mg, then 1 mg), which ZYP describes as about $160 a month. The tirzepatide starter is $450 for two months (2.5 mg, then 5 mg), about $225 a month, with a three-month version available. After the starter, each order is priced on how long that supply will last at your dose, so a higher dose costs more per month; semaglutide is capped at $350 per order. ZYP says month-to-month supplies are available at every dose, but it doesn't publish those prices. Needle-free options are tirzepatide dissolving tablets at $250 for a 30-day supply (3, 4 or 5 mg) and chewable 3 mg tablets at $199 for 30, or $499 for 90. Prices include injection supplies, cold-pack shipping and unlimited messaging, with no membership fee. Affirm financing costs slightly more than paying in full, and HSA and FSA cards are accepted. Insurance isn't billed, though a superbill is available. Medication is final sale once shipped, and on prepaid multi-vial plans the most you can get back by canceling before a later vial ships is $100.
Branded vs compounded
Compounded semaglutide and compounded tirzepatide as weekly injections, plus tirzepatide as a daily dissolving tablet or a chewable tablet. Prescriptions are filled by licensed 503A compounding pharmacies that ZYP says check the potency of each batch, though the pharmacies aren't named. Its standard formulation adds vitamin B6, mainly for nausea, with a B12 and glycine version available for a higher price. Compounded drugs are not FDA-approved, and ZYP says brand-name Wegovy and Zepbound are the first-line choice when available and covered; it doesn't prescribe the brand-name products itself. A search of the FDA warning-letter database for ZYP Medical returned no letters.
Pros and watch-outs
What we like
- Free hour-long first consult with the provider you'll keep
- Direct text access to the same nurse practitioner
- Slow titration with in-between doses
- Needle-free tirzepatide tablets at $250 a month
- No membership fee; HSA and FSA accepted
Watch-outs
- Only seven states
- Injectable starters must be prepaid
- Refill prices vary with dose and aren't published
- One provider means limited cover if he's unavailable
- Compounding pharmacies aren't named; all sales final
Best for
People in Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado or Arizona who want one consistent provider, a long first visit and flexible compounded dosing.
Who should look elsewhere
Anyone outside its seven states, buyers who want a flat monthly price at every dose, or people who want brand-name medication or insurance billing.
The evidence behind what ZYP Medical prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- Tirzepatide vs semaglutide for weight loss: what the trials actually support
Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.
- Oral tirzepatide: the honest status of a pill that does not exist yet
There is no FDA-approved oral tirzepatide. Here is why an oral peptide is hard, what the 'oral tirzepatide' sold online really is, and the oral incretins that actually exist.
- Compounded vs branded GLP-1: regulatory status, sourcing and the evidence
Compounded GLP-1 isn't FDA-approved, the shortage exception behind it ended in 2025, the FDA moved against mass-marketed copies in 2026, and the trial data belong to the branded product. Here's the precise picture.
- 503A vs 503B compounding pharmacies: what the difference actually buys you
Both make drugs the FDA has never approved. Only one must meet CGMP, gets inspected on a schedule, and appears in a public table with its inspection outcomes.
How ZYP Medical compares
A few alternatives worth a look, depending on what you’re optimizing for.
ShedA wide range of GLP-1 formats (injection, drops, lozenges, microdose)
See Shed →
Live VitalPairing a GLP-1 with a wider peptide and longevity protocol
See Live Vital →
JM Integrated HealthPeople in one of its eight states who want the same clinician at every visit and are comfortable paying the pharmacy separately for medication
See JM Integrated Health →
More GLP-1 telehealth reviews: Center for Medical Weight Loss (CMWL)Better Med SpaBeyondMDBiltRxBlivBlue Sky MD
Pharmacology & mechanisms
How we assessed this. This review reflects Aminoscope’s own read of ZYP Medical’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How much does ZYP Medical cost?
- The semaglutide starter is $399 for 10 weeks and the tirzepatide starter $450 for two months, both paid up front. Later orders are priced by dose and supply. Tirzepatide dissolving tablets are $250 for 30 days, and chewable tablets $199 for 30.
- Is the first consult free?
- The weight-loss page says every new plan starts with a free, one-hour consult with Josh Peterson, FNP-C. The same page also lists a $50 Deep Dive and a $29.99 Power Consult, so confirm which applies when you book.
- Which states does ZYP Medical serve?
- Weight-loss care is available to residents of Nebraska, Iowa, South Dakota, Minnesota, Kansas, Colorado and Arizona, by telehealth or in person at the Gretna, Nebraska clinic.
- Can I cancel or get a refund?
- There's no contract, and month-to-month supplies are available, but medication is final sale once it ships. On prepaid multi-vial plans, canceling before a later vial ships returns at most $100.
- Is ZYP Medical legit?
- ZYP Medical is a GLP-1 telehealth service you reach through a video visit with a clinician. The medications it names are Compounded semaglutide and Compounded tirzepatide. Its stated availability: 7 states (NE, IA, SD, MN, KS, CO, AZ). What it publishes up front: Tirzepatide tablets $250 per 30-day supply; injectable starters prepaid ($399 semaglutide, $450 tirzepatide); refills priced by dose. It is cash-pay and states it does not bill insurance. Those are the provider's own published claims rather than checks we could run ourselves, so get the ones that matter to you confirmed in writing before you pay.
- Is ZYP Medical expensive compared with other GLP-1 telehealth providers?
- ZYP Medical publishes a starting figure of $250/mo. Across the 87 GLP-1 telehealth providers we review that publish a single monthly figure, those run $49 to $399 with a median of $190, which puts ZYP Medical above the median. The other 101 GLP-1 telehealth providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.