LifeMD vs SkinnyRx
Brand-name GLP-1s inside LifeMD's primary-care program against SkinnyRx's compounded cash plan with a $99 first month.
Short answer
LifeMD prescribes brand-name drugs with a $149 monthly program fee after a $39 first month, plus medication, about $298 a month on the Wegovy pill, and checks your insurance. SkinnyRx sells compounded semaglutide and tirzepatide, $99 for the first injection month, with the ongoing price shown after signup. SkinnyRx has an FDA warning letter.
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Is LifeMD or SkinnyRx better?
LifeMD is a video-based practice with labs included and an insurance team; it excludes government coverage from the GLP-1 program and keeps program fees if your insurer later denies the drug. SkinnyRx is cash-pay, contract-free and quick, with injections or under-the-tongue tablets, but it doesn't show the month-two price before signup and its orders become non-refundable once fulfillment starts. Compounded drugs aren't FDA-approved. SkinnyRx received FDA warning letter 717989 in February 2026, linked below.
How they differ
- Published up front
LifeMD
Wegovy from $149/mo (pill) or $199 (pen), plus a separate $149/mo program fee — $39 in month oneSkinnyRx
From $99 for the first month; ongoing price shown after signup; cancel anytime- Insurance
LifeMD
Works with insuranceSkinnyRx
Cash-pay only- How you're seen
LifeMD
Video visitSkinnyRx
Video visit / Async intake- Medications
LifeMD
Branded medicationSkinnyRx
Compounded semaglutide, Compounded tirzepatide- FDA warning letter
LifeMD
None on recordSkinnyRx
| LifeMD | SkinnyRx | |
|---|---|---|
| Published up front | Wegovy from $149/mo (pill) or $199 (pen), plus a separate $149/mo program fee — $39 in month one | From $99 for the first month; ongoing price shown after signup; cancel anytime |
| Insurance | Works with insurance | Cash-pay only |
| How you're seen | Video visit | Video visit / Async intake |
| Medications | Branded medication | Compounded semaglutide, Compounded tirzepatide |
| FDA warning letter | None on record | Warning letter 717989 |
What each one costs and includes
Month-to-month prices a new patient can buy, with any required membership counted in. First-month promotions and prepaid averages are labeled as such.
- First full month
LifeMD
$39 the first month, then a $149 monthly program fee plus medication: about $298 a month on the Wegovy pill or $348 on the pen at cash pricesSkinnyRx
$99 for the first month of injections, or $149 to $199 for tablets; the price from month two appears only after you create an account- Once you're on a steady dose
LifeMD
About $448 a month on a Zepbound vial; cash prices for higher doses aren't publishedSkinnyRx
Not shown before signup, so get the renewal price in writing- What the fee covers
LifeMD
Clinician visits, prescriptions, coaching and required lab work; medication is billed separatelySkinnyRx
Provider review and medication, with each compounded lot sent for third-party testing- Medications
LifeMD
Brand-name: the Wegovy pill and pen, Foundayo, Zepbound, Ozempic and Saxenda, plus an oral Triple Therapy optionSkinnyRx
Compounded semaglutide and tirzepatide as weekly injections or daily under-the-tongue tablets- Insurance
LifeMD
Its team checks drug coverage (average approved copay $0 to $25); the program fee is never covered; Medicare, Medicaid and TRICARE are excluded from the GLP-1 programSkinnyRx
Cash-pay; FSA/HSA cards and Affirm financing accepted; no insurance, Medicare or Medicaid- Commitment and refunds
LifeMD
Cancel at any time; program fees aren't refunded if insurance later denies the drugSkinnyRx
Auto-renews; cancel at least five days before renewal; non-refundable once fulfillment starts- How care works
LifeMD
Video visits inside a broader telehealth practice, with required labs and coachingSkinnyRx
Online intake with a provider decision usually inside 24 hours; video only where the state requires it- Look elsewhere if
LifeMD
You're on Medicare, Medicaid or TRICARE, or you're chasing the lowest cash priceSkinnyRx
You want to compare monthly costs before signing up, want a named pharmacy, or live in Alabama, Louisiana or Mississippi
| LifeMD | SkinnyRx | |
|---|---|---|
| First full month | $39 the first month, then a $149 monthly program fee plus medication: about $298 a month on the Wegovy pill or $348 on the pen at cash prices | $99 for the first month of injections, or $149 to $199 for tablets; the price from month two appears only after you create an account |
| Once you're on a steady dose | About $448 a month on a Zepbound vial; cash prices for higher doses aren't published | Not shown before signup, so get the renewal price in writing |
| What the fee covers | Clinician visits, prescriptions, coaching and required lab work; medication is billed separately | Provider review and medication, with each compounded lot sent for third-party testing |
| Medications | Brand-name: the Wegovy pill and pen, Foundayo, Zepbound, Ozempic and Saxenda, plus an oral Triple Therapy option | Compounded semaglutide and tirzepatide as weekly injections or daily under-the-tongue tablets |
| Insurance | Its team checks drug coverage (average approved copay $0 to $25); the program fee is never covered; Medicare, Medicaid and TRICARE are excluded from the GLP-1 program | Cash-pay; FSA/HSA cards and Affirm financing accepted; no insurance, Medicare or Medicaid |
| Commitment and refunds | Cancel at any time; program fees aren't refunded if insurance later denies the drug | Auto-renews; cancel at least five days before renewal; non-refundable once fulfillment starts |
| How care works | Video visits inside a broader telehealth practice, with required labs and coaching | Online intake with a provider decision usually inside 24 hours; video only where the state requires it |
| Look elsewhere if | You're on Medicare, Medicaid or TRICARE, or you're chasing the lowest cash price | You want to compare monthly costs before signing up, want a named pharmacy, or live in Alabama, Louisiana or Mississippi |
LifeMD
- Access
- Wegovy from $149/mo (pill) or $199 (pen), plus a separate $149/mo program fee — $39 in month one
- Medications
- Branded
- Insurance
- Works with insurance
- Visit
- Video visit
What we like
- FDA-approved brand-name medication, including the Wegovy and Foundayo pills
- Insurance team checks your coverage and copay before you fill
- Lab work included in the program fee unless done in the past year
Watch-outs
- The $149 monthly program fee sits on top of medication and is never covered by insurance
- Medicare, Medicaid, TRICARE and other government coverage are excluded from the GLP-1 program
Pick LifeMD if: You want a brand-name drug and general primary care with it.
Check LifeMD availability →Read the full LifeMD review →
SkinnyRx
Partner- Access
- From $99 for the first month; ongoing price shown after signup; cancel anytime
- Medications
- Semaglutide · Tirzepatide · Oral
- Insurance
- Cash-pay
- Visit
- Video visit / Async intake
What we like
- Low first-month entry price: $99 for injections
- Injection or daily tablet for both semaglutide and tirzepatide, with microdosing on most
- Provider decision usually within 24 hours, video visit only where the state requires one
Watch-outs
- Only first-month prices are published; the month-two price appears after signup
- Non-refundable once fulfillment starts, and promotional discounts can be reversed if you cancel early
Pick SkinnyRx if: You want a compounded plan you can start cheaply and cancel, and you'll confirm the renewal price.
Check SkinnyRx availability →Read the full SkinnyRx review →Want the full field? See every option in our GLP-1 providers roundup, or narrow by tirzepatide / semaglutide and price.