NiceRx review

What it is

NiceRx LLC, based in Boca Raton, Florida and founded in 2022 by Rob Stransky, is a telehealth prescriber running three product lines: anti-aging (NAD⁺ injection, NAD⁺ nasal spray, NAD⁺ face cream, glutathione injection, B12 and MIC+B12), strength (sermorelin injection and sermorelin tablets), and weight loss (compounded semaglutide at $199/mo after a $99 first month, compounded tirzepatide at $299/mo after $199, plus microdose versions and a starter bundle). It is LegitScript approved and available in 46 states.

How it works

Quiz-led and asynchronous, with an unusually complete commercial disclosure. NiceRx enumerates exactly where it does not operate — Alaska, Mississippi, New Jersey and Kansas — rather than leaving state coverage to intake, which is more than most of this board offers. It states that plans include the provider's visit, the medication and free shipping, with an initial provider visit and up to one monthly follow-up covered, and that every batch is tested for sterility and potency. On the GLP-1 side it commits to the same price at every dose with no higher-dose surcharge, which is the kind of promise worth checking against the anti-aging line, because the NAD⁺ pages present a first-month promotional rate and a standing rate rather than a dose statement. Two gaps. NiceRx does not name its compounding pharmacy, so batch testing is a claim about a process rather than a facility you can look up. And the brand's own history is a source of confusion: it built its name as a prescription-savings and patient-assistance service, and readers arriving from that reputation should understand they are now buying compounded medication directly rather than being helped to access a manufacturer's program.

Pricing transparency

NAD⁺ nasal spray is $69 for the first month then $119/mo; NAD⁺ injection is $189 for the first month then $239/mo. Both figures are stated on their own product pages with the promotional and standing rates shown together, which is the honest way to present a first-month discount. There is also an NAD⁺ face cream and a glutathione injection on the same anti-aging shelf, and sermorelin in injection and tablet form on the strength shelf. The pricing to plan around is the standing rate, not the promotional one — a $50-off first month is a $50 saving, not a price. On the weight-loss side, semaglutide is $199/mo and tirzepatide $299/mo with the same first-month structure and an explicit flat-dose commitment, and the price is stated to include the provider visit, medication and free shipping. None of the GLP-1 figures is an NAD⁺ price.

Branded vs compounded

Compounded; not FDA-approved. Prescription required only if a licensed provider finds it appropriate. NiceRx sells compounded preparations only — no brand-name products — and while it states that every batch is tested for sterility and potency, compounded preparations are not reviewed by the FDA for purity and potency the way approved drugs are, and the compounding pharmacy is not named. On evidence, the anti-aging shelf is where the claims outrun the data. Injected and intranasal NAD⁺ have no controlled human outcome trials; the single human intravenous study was a pharmacokinetic pilot showing infused NAD⁺ clears from plasma quickly. The topical face cream has less support again — there is no controlled human outcome evidence for topical NAD⁺ at all. The NAD⁺ forms with human data are the oral precursors nicotinamide riboside and nicotinamide mononucleotide, which reliably raise blood NAD⁺ levels; that is a raised biomarker, not a demonstrated clinical benefit, and it is worth understanding that the routes NiceRx sells are not the routes that were studied. Glutathione has essentially no controlled human outcome data. Sermorelin is the strongest name on the menu: a GHRH analogue acting on a real, well-described pituitary axis, with thin long-term human outcome data. Individual results vary.

Pros and watch-outs

The evidence behind what NiceRx prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• NAD+ precursors (NR and NMN): what the human trials actually show

  They raise NAD+ and look safe short-term — but human evidence is surrogate-marker level, and no trial shows they extend healthspan.

• Glutathione: the master antioxidant, and where the evidence actually is

  Oral glutathione really does raise your body stores (a 6-month RCT proved it) — but the longevity and detox claims are unproven, skin-lightening is modest, and IV glutathione is the most marketed, least evidenced route. The precursors may be the smarter bet.

• Sermorelin: a real GHRH drug, read against the anti-aging pitch

  An approved growth-hormone-releasing analog with a pediatric track record — and a longevity case built more on biomarkers than outcomes.

How NiceRx compares

A few alternatives worth a look, depending on what you’re optimizing for.

• NMNova MD

  NAD⁺ buyers who want the concentration and vial size stated, not just a monthly fee

  See Nova MD →
• NHNucore Health

  A flat, any-dose NAD⁺ price with no membership fee, nationwide

  See Nucore Health →
• OHObu Health

  NAD⁺ injections from a platform that names the pharmacies preparing them

  See Obu Health →