Sesame review
Upfront cash marketplace
A cash-pay telehealth marketplace where you book a specific clinician at upfront prices, with medication billed separately.
Our verdict
Sesame is different from the other names here: it's a cash-pay marketplace where you pick and book a specific clinician at transparent, upfront visit prices, no insurance or membership needed. That transparency and choice are the appeal — just know the visit and the medication are separate costs, and what you're prescribed can be branded, compounded, or oral depending on the clinician.
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At a glance
- Category
- GLP-1 telehealth
- Access
- Cash-pay, no insurance required
- Medications
- Semaglutide · Tirzepatide · Oral · Branded
- Insurance
- Cash-pay, no insurance
- Visit
- Video visit
- Updated
- July 2026
Popular alternative
Enhance MD
Lab-guided treatment under ongoing physician oversight
Check Enhance MD availability →What it is
Sesame is a cash-pay telehealth marketplace. Instead of one house program, you book directly with a specific clinician at transparent, upfront prices — including weight-loss visits and GLP-1 programs — with no insurance or membership required.
How it works
You browse clinicians, see the visit price up front, and book the one you want by video. Because it's a marketplace, the experience and the exact GLP-1 approach vary by clinician rather than following a single standardized program — more choice, less uniformity.
Pricing transparency
Sesame is cash-pay with no insurance required, and visit prices are shown upfront when you book — that upfront transparency is its main selling point. Note that the medication is billed separately from the visit, so the booking price you see is not the all-in cost of treatment; budget for the drug on top.
Branded vs compounded
Depending on the clinician and program, Sesame can involve FDA-approved branded GLP-1s, compounded semaglutide or tirzepatide, or an oral option — with the medication billed separately from the visit. Branded and compounded are not equivalent: compounded products are not FDA-approved, so confirm exactly what you're being prescribed.
Pros and watch-outs
What we like
- Transparent, upfront visit prices
- Book a specific clinician of your choice
- No insurance or membership required
- Branded, compounded, and oral options exist across the marketplace
Watch-outs
- Medication is billed separately — the visit price isn't the all-in cost
- Experience and GLP-1 approach vary by clinician, not one standard program
- Compounded options aren't FDA-approved; confirm what you're prescribed
Best for
People who want to choose their own clinician at upfront cash prices and don't need insurance or a fixed house program.
Who should look elsewhere
Anyone who wants insurance billing or one standardized, program-style experience with medication bundled in.
How Sesame compares
A few alternatives worth a look, depending on what you’re optimizing for.
FoundPutting insurance benefits toward GLP-1 treatment
See Found →
Henry MedsSimple flat-fee compounded access without insurance
See Henry Meds →
PlushCareBranded GLP-1s billed through insurance
See PlushCare →
Access & cost · Reviewed and last verified July 2026
How we assessed this. This review reflects Aminoscope’s own read of Sesame’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How does Sesame's pricing work?
- Sesame is cash-pay with no insurance or membership required, and it shows visit prices upfront when you book. The medication is billed separately, so the visit price you see isn't the all-in cost of treatment.
- Does Sesame offer branded or compounded GLP-1?
- Both can appear on Sesame, along with oral options, depending on the clinician and program you book. Branded GLP-1s are FDA-approved; compounded semaglutide and tirzepatide are not, so confirm exactly what a given clinician prescribes.
- Does Sesame take insurance?
- No — Sesame is a cash-pay marketplace with no insurance required. Its pitch is transparent, upfront cash prices for the visit rather than insurance billing.