AlyveRx review

What it is

AlyveRx is the consumer brand of Alyve, Inc., which lists an address in Mount Dora, Florida, and a mailing address in Zellwood, Florida. Its terms describe it as a clinical infrastructure and managed services organization: it doesn't employ physicians or practice medicine, and independent licensed providers make all medical decisions through affiliated professional groups in the states where they're licensed. Prescriptions are filled by a network of licensed pharmacies and compounding facilities that it doesn't name, and you can ask for yours to go to a pharmacy of your choice. Besides weight loss, it sells NAD⁺, glutathione and sermorelin, with drop versions of those listed as coming soon, plus sexual-health treatment. Its founder and chief scientist, Steve Kushner, developed the PermeAct delivery technology behind the drops. It says it has treated more than 10,000 patients. The site doesn't list which states it serves or display a LegitScript seal.

How it works

You take an online assessment covering your health history, lifestyle and goals. A licensed provider reviews it and recommends a plan if treatment is appropriate; the terms say providers also handle any good-faith exams required before treatment. There's no scheduled visit in the standard process. If you're approved, medication ships free and discreetly, and the site says it arrives in under 48 hours. Injections come as a 5 mL vial with a home kit. Drops are taken under the tongue instead of injected. Afterward you get regular check-ins, on-demand medical support and help with side effects, with support available by email. Care runs entirely outside insurance, so no prior authorization is needed or available, and the company won't file claims for you.

Pricing transparency

Compounded semaglutide injections start at $183 a month and semaglutide drops at $203. Tirzepatide drops start at $249, and tirzepatide injections at $283 on the product page, while the site's menu lists them at $329 a month, which suggests the lowest prices apply to longer plans and $329 is closer to the single-month price. The exact plan lengths and terms appear only at checkout, and the product pages don't say whether the price changes as your dose rises. Brand-name drugs are sold at cash prices: Ozempic and Mounjaro from $1,395 a month and Wegovy from $1,695. Plans are recurring subscriptions billed at the frequency shown at checkout and renew until you cancel in your account settings before the next billing date. Charges are generally non-refundable once an order is processed, with exceptions for damage, loss in transit, or a treatment becoming unavailable, in which case you may get a prorated refund for the unshipped part of a prepaid plan, an alternative or a credit. Insurance isn't accepted.

Branded vs compounded

AlyveRx's providers prescribe compounded semaglutide and tirzepatide as weekly injections or as sublingual drops, and brand-name Ozempic, Wegovy and Mounjaro. The company says its PermeAct technology works by briefly opening pathways in tissue to improve absorption and that it has been tested in lab, animal and human studies, including placebo-controlled trials, with publications in several journals. Those studies involve its technology in other products such as nutrition formulas, so they don't show how well a GLP-1 drop works. The FDA-approved pill forms of semaglutide are swallowed tablets, not drops. Compounded drugs are not FDA-approved, which its FAQ notes. The "11-20%" weight-loss range on its homepage is based on studies of the highest doses of the branded drugs. A search of the FDA warning-letter database under Alyve and AlyveRx returned no letters.

Pros and watch-outs

The evidence behind what AlyveRx prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• What the semaglutide weight-loss trials actually showed

  STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.

• Tirzepatide vs semaglutide for weight loss: what the trials actually support

  Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.

• Compounded vs branded GLP-1: regulatory status, sourcing and the evidence

  Compounded GLP-1 isn't FDA-approved, the shortage exception behind it ended in 2025, the FDA moved against mass-marketed copies in 2026, and the trial data belong to the branded product. Here's the precise picture.

• GLP-1 pill vs injection: what you trade for swallowing it

  Oral semaglutide 50 mg matched the injection to within 0.2 of a percentage point — but not at the approved dose, and the daily fasting protocol is the cost nobody mentions.

How AlyveRx compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Shed

  A wide range of GLP-1 formats (injection, drops, lozenges, microdose)

  See Shed →
• Willow

  Buyers who want every dose priced and the pharmacies named, and will pay more for it

  See Willow →
• Recovery Delivered

  People who want a real video visit every month and a published price for every dose

  See Recovery Delivered →

More GLP-1 telehealth reviews: Rehydra+ Wellness · AurenRx · Vyvron · Lighter You · Pallas Health · AHBARx