Metabolyz review

What it is

Metabolyz is owned and run by The Westview Drive Co Inc and lists an office at 401 B Street in San Diego, California; its terms apply Delaware law. It describes itself as a concierge telehealth platform that connects patients with independent, board-certified providers and state-licensed compounding pharmacies, and says it doesn't practice medicine, write prescriptions or dispense drugs. Its terms say the subscription price bundles the pharmacy's fee for the drug, the medical group's fee for the provider and the platform's own fee, but the site doesn't name the medical group, the providers or the pharmacies; it says medication is compounded in state-licensed 503A and 503B pharmacies in the U.S. Beyond weight loss, it sells compounded NAD⁺, sermorelin and tesamorelin. It's self-pay only. Support is by email, phone or text, weekdays from 9 a.m. to 5 p.m. Pacific.

How it works

You start with a short online eligibility assessment, which the site says takes about two minutes. A licensed clinician reviews your history and, if treatment is appropriate, authorizes a GLP-1 protocol that a partner compounding pharmacy prepares and ships in unmarked, temperature-controlled packaging, with shipping included. For semaglutide, the site lists adults with a BMI of 27 or more, or 25 or more with a weight-related condition, as the usual fit, and rules out anyone with a personal or family history of medullary thyroid cancer or MEN 2, pregnancy or active pancreatitis. Dosing starts low and steps up monthly. After that, care runs through structured check-ins and direct messaging with your provider and a coach who works on nutrition, movement, sleep and habits. The peptide programs follow the same route; for sermorelin, the provider may order baseline IGF-1 labs and typically runs it in courses.

Pricing transparency

Metabolyz gives two different answers on price. Its peptide page lists compounded semaglutide "from $149/mo", tirzepatide from $175 and the lower-dose GLP-1 protocol from $99, along with NAD⁺ from $169 and tesamorelin from $249. Its FAQ, on the homepage and every program page, says pricing is reviewed during your consultation in the context of your protocol and program length and isn't published on public pages. The site doesn't say whether the listed figures are first-month, longer-plan or starting-dose prices, and sermorelin has no price at all. The homepage describes one monthly membership that bundles the medical evaluation, supervision and coaching, with no hidden fees. Under its terms, you're charged when you order and every 30 days after until you cancel, with a reminder five to seven days before each charge, and you can cancel up to 48 hours before the next charge. A prescription order can be canceled only within 24 hours of placing it. Refunds are limited to cases such as a provider declining to prescribe, a prescription the pharmacist can't verify, or a wrong or damaged product; you aren't charged for treatment if you aren't approved.

Branded vs compounded

Providers can prescribe compounded semaglutide and compounded tirzepatide as weekly injections, plus a lower-dose GLP-1 protocol aimed at body composition rather than aggressive weight loss, prepared by partner compounding pharmacies in the U.S. The site states that compounded medications are not FDA-approved and that their safety, effectiveness and quality haven't been verified by the FDA. The trial outcomes it refers to come from studies of the brand-name drugs. Brand-name Wegovy, Ozempic, Zepbound and Mounjaro aren't offered. Its peptide menu includes sermorelin and tesamorelin, plus NAD⁺. Metabolyz doesn't display a LegitScript seal. A search of the FDA warning-letter database under its brand name and its company name returned no letters.

Pros and watch-outs

The evidence behind what Metabolyz prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• What the semaglutide weight-loss trials actually showed

  STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.

• Tirzepatide vs semaglutide for weight loss: what the trials actually support

  Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.

• Compounded vs branded GLP-1: regulatory status, sourcing and the evidence

  Compounded GLP-1 isn't FDA-approved, the shortage exception behind it ended in 2025, the FDA moved against mass-marketed copies in 2026, and the trial data belong to the branded product. Here's the precise picture.

• Sermorelin benefits: does it work? What the trials show

  A real GHRH drug, read against the anti-aging pitch: an approved growth-hormone-releasing analog with a pediatric track record, and a longevity case built more on biomarkers than outcomes.

• Tesamorelin (Egrifta): what it's actually FDA-approved for, and the evidence

  A real, approved GHRH analog — for HIV-associated lipodystrophy specifically. What the pivotal trials showed, and why the longevity use is an extrapolation.

• NAD+ precursors (NR and NMN): what the human trials actually show

  They raise NAD+ and look safe short-term, but human evidence is surrogate-marker level, and no trial shows they extend healthspan.

How Metabolyz compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Shed

  A wide range of GLP-1 formats (injection, drops, lozenges, microdose)

  See Shed →
• Live Vital

  Pairing a GLP-1 with a wider peptide and longevity protocol

  See Live Vital →
• LVNG RX

  Cash buyers who want a compounded GLP-1, a lower-dose option or growth-hormone peptides from one platform

  See LVNG RX →

More GLP-1 telehealth reviews: LeanDose · LevelsRx · LifeRx.md · Livea · 50 Stars Health · Loozy