Is Rx.com really $146 a month?

Only on a six-month plan paid upfront, which is $875 in one charge. Month-to-month semaglutide is $175, and three months is $165/month ($495). Tirzepatide runs $285 month-to-month, $265 across three months and $259 across six ($1,550). To Rx.com's credit the asterisk is right there — "*on a 6-month plan" sits under the headline figure on the homepage, and the full table is on the weight-loss page — so this is a criticism of which number leads, not of the disclosure behind it.

Does Rx.com actually offer TRT, hair loss or women's health treatment?

Not that we could reach. Its homepage advertises testosterone therapy, dermatology, hair regrowth, women's health and primary care with "Get started" buttons, and every one of those links goes to a path under /out/ that redirects straight back to rx.com's homepage. We followed nine such links with curl and again in a real browser, and none reached a service, an intake or a third party. The only working program on the site is weight loss.

Is the ED page Rx.com's own service?

No. It is a comparison page. Its "top pick" is QUAD by MEDVi at $114/month, with Hims and Peter MD listed beneath — all three are separate companies we cover independently — and its three "Get started" buttons point at /out/quad, /out/hims-ed and /out/petermd-ed, all of which redirect back to the homepage. If you want ED treatment, go to a provider that prescribes it rather than a page that ranks other providers.

Which pharmacy fills the prescription?

Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650, named in the footer of every page along with the provider network, MD Integrations. That is better disclosure than most of this board manages, where the pharmacy is usually just "a partner compounding pharmacy" and never named. Manifest is the same facility Nex Gen Health Rx names, if you are comparing the two.

How many states does Rx.com serve?

The site answers this two ways. Its homepage banner says "Licensed Providers in all 50 States"; its weight-loss program page says "49 states served," and its plan footnote says "Not available in Alaska." The program-page figure is the specific one and is consistent with the Alaska exclusion, so 49 is the number to work from — but a service should not contradict itself on coverage, and if you are in Alaska the homepage would tell you the wrong thing.

Rx.com is a GLP-1 telehealth service you reach through an online questionnaire and an online intake a clinician reviews. The medications it names are Compounded semaglutide and Compounded tirzepatide. Its stated availability: 49 states (not Alaska) — the homepage says all 50. What it publishes up front: Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named. It is cash-pay and states it does not bill insurance. It displays a LegitScript certification claim, which we record as a claim and not as a verified fact: LegitScript's public checker is gated and returns the same page for any domain put into it, so no one can reproduce a check from it. Those are the provider's own published claims rather than checks we could run ourselves, so get the ones that matter to you confirmed in writing before you pay.

Is Rx.com expensive compared with other GLP-1 telehealth providers?

Rx.com publishes a starting figure of $175/mo. Across the 52 GLP-1 telehealth providers we review that publish a single monthly figure, those run $49 to $269 with a median of $179, which puts Rx.com below the median, toward the cheaper end. The other 31 GLP-1 telehealth providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Rx.com review

Documented well, mostly shopfront

One real program, documented better than almost anything on this board — and five advertised categories that go nowhere.

Our verdict

Rx.com's weight-loss program is among the best-documented on this board: it names the dispensing pharmacy with a street address, names the provider network, prints the whole plan table, and publishes the GLP-1 boxed warning in full — which most of this category quietly omits. But treat the rest of the site as advertising rather than inventory. Its homepage sells six categories with live buttons, and every one of them redirects straight back to the homepage. The ED page isn't a service at all but a comparison page recommending three competitors. Rx.com calls its weight-loss program "our own program, not a referral" — which reads differently once you find that nothing else here is either.

Disclosure: Aminoscope is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

Check availability →Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named

At a glance

Category: GLP-1 telehealth
Access: Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named
Medications: Compounded semaglutide · Compounded tirzepatide
Insurance: Cash-pay, no insurance
Visit: Quiz intake / Async intake
Availability: 49 states (not Alaska) — the homepage says all 50
LegitScript: Claimed by provider
Updated: September 2026

What it is

Two businesses under one domain, operated by Rx Platform LLC. The first is a free prescription discount card and coupon service for retail pharmacies — the original business, and the bulk of the homepage. The second, newer one is a compounded GLP-1 weight-loss program: an online visit with a licensed provider, medication at any prescribed dose, injection supplies and cold shipping under one price. The site describes itself as a marketplace platform connecting patients with independently licensed providers, states that it does not dispense medication or provide medical services, and displays a LegitScript seal whose id resolves against the issuer.

How it works

Asynchronous, with a two-minute eligibility check before payment and a licensed provider review usually within 24 hours; some states add a short video visit. Two disclosures put it ahead of most of this board: medications are dispensed by Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650 — named, addressed, and the same 503A facility Nex Gen Health Rx uses — and the provider network is named as MD Integrations. It also states that plans do not renew automatically and that refills are sent only after you check in with the care team. ⚠ Coverage is stated two ways on two pages: "Licensed Providers in all 50 States" on the homepage against "49 states served" and "Not available in Alaska" on the program page.

Pricing transparency

Fully tabled, with the prepay discount visible rather than implied. Compounded semaglutide is $175/month billed monthly, $165/month across three months ($495 upfront) or $146/month across six ($875 upfront). Compounded tirzepatide is $285, $265 and $259 on the same three lengths ($1,550 for six months). One price covers the visit, the medication at any dose, injection supplies and shipping, and there is no membership fee. ⚠ The $146 that runs across the top of every page is the six-month rate; the site labels it "*on a 6-month plan" in the same block, which is the honest version of this pattern, but the month-to-month figure a first-time buyer actually pays is $175. If you are not approved, you are not charged for medication.

Branded vs compounded

Compounded semaglutide and compounded tirzepatide, at one price per dose. Rx.com does something on this page that very little of this category does: it prints the boxed warning — that semaglutide and tirzepatide caused thyroid C-cell tumors in rodent studies, with the medullary thyroid carcinoma and MEN2 contraindications spelled out — alongside a full list of common and serious adverse effects. On the evidence: the outcome data for these molecules is strong and belongs to the branded products, not to compounded copies, which are not FDA-approved and are not assessed by the FDA for potency, purity or consistency. Rx.com states this correctly and repeatedly.

Pros and watch-outs

What we like

Dispensing pharmacy named with a street address (Manifest Pharmacy, Greer, SC) and provider network named (MD Integrations)
Full plan table published — 1, 3 and 6 months, with the upfront charge shown
Publishes the GLP-1 boxed warning and adverse-effect list in full, which most of this board omits
LegitScript seal id resolves against the issuer
No automatic renewal; refills only after a check-in, and no medication charge if you are not approved

Watch-outs

Five advertised categories — TRT, dermatology, hair loss, women's health, primary care — have buttons that redirect back to the homepage
The ED page is a comparison page recommending competitors, and its three CTAs are dead as well
Contradicts itself on coverage: "all 50 States" on the homepage, "49 states" and "not available in Alaska" on the program page
The $146 headline is the six-month prepay rate; month-to-month is $175

Best for

Buyers who want a compounded GLP-1 from a service that names its pharmacy, its provider network and its risks, and who are only here for weight loss.

Who should look elsewhere

Anyone drawn by the TRT, hair, skin, women's health or ED categories on the homepage — none of those buttons reaches a service.

The evidence behind what Rx.com prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

What the semaglutide weight-loss trials actually showed
STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.
Tirzepatide vs semaglutide for weight loss: what the trials actually support
Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.

How Rx.com compares

A few alternatives worth a look, depending on what you’re optimizing for.

Idgie Health
One menu covering GLP-1, NAD⁺, sermorelin and hair care with the pharmacy named
See Idgie Health →
No BS RX
Readers who want the month-to-month price first and every plan length beside it
See No BS RX →
Renlo Health
A flat monthly GLP-1 price with the provider group, pharmacy and 503A basis all named
See Renlo Health →

Compare all providers side by side →

More GLP-1 telehealth reviews: Sprout HealthYucca HealthSesameWellorithmRxSpan MDSuperior Remedies

Nadia Feldman

Access & cost · Reviewed and last verified September 2026

How we assessed this. This review reflects Aminoscope’s own read of Rx.com’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

Is Rx.com really $146 a month?: Only on a six-month plan paid upfront, which is $875 in one charge. Month-to-month semaglutide is $175, and three months is $165/month ($495). Tirzepatide runs $285 month-to-month, $265 across three months and $259 across six ($1,550). To Rx.com's credit the asterisk is right there — "*on a 6-month plan" sits under the headline figure on the homepage, and the full table is on the weight-loss page — so this is a criticism of which number leads, not of the disclosure behind it.
Does Rx.com actually offer TRT, hair loss or women's health treatment?: Not that we could reach. Its homepage advertises testosterone therapy, dermatology, hair regrowth, women's health and primary care with "Get started" buttons, and every one of those links goes to a path under /out/ that redirects straight back to rx.com's homepage. We followed nine such links with curl and again in a real browser, and none reached a service, an intake or a third party. The only working program on the site is weight loss.
Is the ED page Rx.com's own service?: No. It is a comparison page. Its "top pick" is QUAD by MEDVi at $114/month, with Hims and Peter MD listed beneath — all three are separate companies we cover independently — and its three "Get started" buttons point at /out/quad, /out/hims-ed and /out/petermd-ed, all of which redirect back to the homepage. If you want ED treatment, go to a provider that prescribes it rather than a page that ranks other providers.
Which pharmacy fills the prescription?: Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650, named in the footer of every page along with the provider network, MD Integrations. That is better disclosure than most of this board manages, where the pharmacy is usually just "a partner compounding pharmacy" and never named. Manifest is the same facility Nex Gen Health Rx names, if you are comparing the two.
How many states does Rx.com serve?: The site answers this two ways. Its homepage banner says "Licensed Providers in all 50 States"; its weight-loss program page says "49 states served," and its plan footnote says "Not available in Alaska." The program-page figure is the specific one and is consistent with the Alaska exclusion, so 49 is the number to work from — but a service should not contradict itself on coverage, and if you are in Alaska the homepage would tell you the wrong thing.
Is Rx.com legit?: Rx.com is a GLP-1 telehealth service you reach through an online questionnaire and an online intake a clinician reviews. The medications it names are Compounded semaglutide and Compounded tirzepatide. Its stated availability: 49 states (not Alaska) — the homepage says all 50. What it publishes up front: Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named. It is cash-pay and states it does not bill insurance. It displays a LegitScript certification claim, which we record as a claim and not as a verified fact: LegitScript's public checker is gated and returns the same page for any domain put into it, so no one can reproduce a check from it. Those are the provider's own published claims rather than checks we could run ourselves, so get the ones that matter to you confirmed in writing before you pay.
Is Rx.com expensive compared with other GLP-1 telehealth providers?: Rx.com publishes a starting figure of $175/mo. Across the 52 GLP-1 telehealth providers we review that publish a single monthly figure, those run $49 to $269 with a median of $179, which puts Rx.com below the median, toward the cheaper end. The other 31 GLP-1 telehealth providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every GLP-1 provider.