Is Rx.com really $146 a month?

Only on a six-month plan paid upfront, which is $875 in one charge. Month-to-month semaglutide is $175, and three months is $165/month ($495). Tirzepatide runs $285 month-to-month, $265 across three months and $259 across six ($1,550). To Rx.com's credit the asterisk is right there — "*on a 6-month plan" sits under the headline figure on the homepage, and the full table is on the weight-loss page — so this is a criticism of which number leads, not of the disclosure behind it.

Does Rx.com actually offer TRT, hair loss or women's health treatment?

Not in any way you can use. Its homepage advertises testosterone therapy, dermatology, hair regrowth, women's health and primary care with "Get started" buttons, and every one of those buttons takes you straight back to the homepage. None of the nine such buttons leads to a service, an intake or a third party. The only working program on the site is weight loss.

Is the ED page Rx.com's own service?

No. It is a comparison page. Its "top pick" is QUAD by MEDVi at $114/month, with Hims and Peter MD listed beneath — all three are separate companies we cover independently — and all three of its "Get started" buttons lead back to the homepage. If you want ED treatment, go to a provider that prescribes it rather than a page that ranks other providers.

Which pharmacy fills the prescription?

Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650, named in the footer of every page along with the provider network, MD Integrations. That is real disclosure; many sellers describe the pharmacy only as "a partner compounding pharmacy" and never name it. Manifest is the same facility Nex Gen Health Rx names, if you are comparing the two.

How many states does Rx.com serve?

The site answers this two ways. Its homepage banner says "Licensed Providers in all 50 States"; its weight-loss program page says "49 states served," and its plan footnote says "Not available in Alaska." The program-page figure is the specific one and is consistent with the Alaska exclusion, so 49 is the number to work from — but a service should not contradict itself on coverage, and if you are in Alaska the homepage would tell you the wrong thing.

Is Rx.com expensive compared with other GLP-1 telehealth providers?

Rx.com publishes a starting figure of $175/mo. Across the 110 GLP-1 telehealth providers we review that publish a single monthly figure, those run $49 to $399 with a median of $189, which puts Rx.com below the median, toward the cheaper end. The other 285 GLP-1 telehealth providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Updated September 2026

Rx.com review

By Aminoscope editorial desk · Aminoscope

Documented well, mostly shopfront

One real program, unusually well documented — and five advertised categories that go nowhere.

Our verdict

Main trade-offs

Five advertised categories — TRT, dermatology, hair loss, women's health, primary care — have buttons that redirect back to the homepage
The ED page is a comparison page recommending competitors, and its three CTAs are dead as well

Disclosure: Aminoscope is reader-supported. We may earn a commission from partner links, at no extra cost to you. This never changes our assessment. How we make money.

Compounded medicines are not FDA-approved. A licensed clinician must assess whether treatment is appropriate; availability does not establish safety or benefit.

Check availability →Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named

Good fit

Buyers who want a compounded GLP-1 from a service that names its pharmacy, its provider network and its risks, and who are only here for weight loss.

Consider other options if

Anyone drawn by the TRT, hair, skin, women's health or ED categories on the homepage — none of those buttons reaches a service.

Cost and care at a glance

Category: GLP-1 telehealth
Published cost: Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named
Medications: Compounded semaglutide · Compounded tirzepatide
Insurance: Cash-pay, no insurance
Visit: Quiz intake / Async intake
Availability: 49 states (not Alaska) — the homepage says all 50
LegitScript: Claimed by provider

Our review in detail

Full assessment

Rx.com's weight-loss program is thoroughly documented: it names the dispensing pharmacy with a street address, names the provider network, prints the whole plan table, and publishes the GLP-1 boxed warning in full — which most of this category quietly omits. But treat the rest of the site as advertising rather than inventory. Its homepage sells six categories with live buttons, and every one of them redirects straight back to the homepage. The ED page isn't a service at all but a comparison page recommending three competitors. Rx.com calls its weight-loss program "our own program, not a referral" — which reads differently once you find that nothing else on the site is a program at all.

What it is

Two businesses under one domain, operated by Rx Platform LLC. The first is a free prescription discount card and coupon service for retail pharmacies — the original business, and the bulk of the homepage. The second, newer one is a compounded GLP-1 weight-loss program: an online visit with a licensed provider, medication at any prescribed dose, injection supplies and cold shipping under one price. The site describes itself as a marketplace platform connecting patients with independently licensed providers, states that it does not dispense medication or provide medical services, and displays a LegitScript seal.

How care works

Asynchronous, with a two-minute eligibility check before payment and a licensed provider review usually within 24 hours; some states add a short video visit. Two disclosures stand out: medications are dispensed by Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650 — named, addressed, and the same 503A facility Nex Gen Health Rx uses — and the provider network is named as MD Integrations. It also states that plans do not renew automatically and that refills are sent only after you check in with the care team. Coverage is stated two ways on two pages: "Licensed Providers in all 50 States" on the homepage against "49 states served" and "Not available in Alaska" on the program page.

Costs, billing and cancellation

Fully tabled, with the prepay discount visible rather than implied. Compounded semaglutide is $175/month billed monthly, $165/month across three months ($495 upfront) or $146/month across six ($875 upfront). Compounded tirzepatide is $285, $265 and $259 on the same three lengths ($1,550 for six months). One price covers the visit, the medication at any dose, injection supplies and shipping, and there is no membership fee. The $146 that runs across the top of every page is the six-month rate; the site labels it "*on a 6-month plan" in the same block, which is the honest version of this pattern, but the month-to-month figure a first-time buyer actually pays is $175. If you are not approved, you are not charged for medication.

Medication and evidence

Compounded semaglutide and compounded tirzepatide, at one price per dose. Rx.com does something on this page that very little of this category does: it prints the boxed warning — that semaglutide and tirzepatide caused thyroid C-cell tumors in rodent studies, with the medullary thyroid carcinoma and MEN2 contraindications spelled out — alongside a full list of common and serious adverse effects. On the evidence: the outcome data for these molecules is strong and belongs to the branded products, not to compounded copies, which are not FDA-approved and are not assessed by the FDA for potency, purity or consistency. Rx.com states this correctly and repeatedly.

Pros and watch-outs

What we like

Dispensing pharmacy named with a street address (Manifest Pharmacy, Greer, SC) and provider network named (MD Integrations)
Full plan table published — 1, 3 and 6 months, with the upfront charge shown
Publishes the GLP-1 boxed warning and adverse-effect list in full
Displays a LegitScript seal with a checkable ID
No automatic renewal; refills only after a check-in, and no medication charge if you are not approved

Watch-outs

Five advertised categories — TRT, dermatology, hair loss, women's health, primary care — have buttons that redirect back to the homepage
The ED page is a comparison page recommending competitors, and its three CTAs are dead as well
Contradicts itself on coverage: "all 50 States" on the homepage, "49 states" and "not available in Alaska" on the program page
The $146 headline is the six-month prepay rate; month-to-month is $175

Best for

Buyers who want a compounded GLP-1 from a service that names its pharmacy, its provider network and its risks, and who are only here for weight loss.

Who should look elsewhere

Anyone drawn by the TRT, hair, skin, women's health or ED categories on the homepage — none of those buttons reaches a service.

Research relevant to Rx.com

Explore the evidence and its limits. Findings apply to the formulation, route and population studied; they do not establish the quality or effectiveness of a provider’s products.

What the semaglutide weight-loss trials actually showed
STEP 1, STEP 4 and SELECT, plus oral and higher-dose semaglutide trials: weight loss, withdrawal, cardiovascular benefit and the limits of comparison.
Tirzepatide vs semaglutide for weight loss: what the trials actually support
SURMOUNT-5 found 20.2% versus 13.7% average weight loss. What that direct comparison supports, which doses it tested, and why newer formulations need separate evidence.

How Rx.com compares

A few alternatives worth a look, depending on what you’re optimizing for.

Belle
People who want a flat price that doesn't rise with the dose and regular dietitian check-ins
See Belle →
EverPrime
Adults comparing longer GLP-1 plans who can confirm the full upfront charge, membership period and renewal terms.
See EverPrime →
Idgie Health
One menu covering GLP-1, NAD⁺, sermorelin and hair care with the pharmacy named
See Idgie Health →

Compare all providers side by side →

More GLP-1 telehealth reviews: Fifty 410Fitness RXFitstryFlorida Weight Loss MDFormBlendsFound Youth

Aminoscope editorial desk

Editorial research

How we assessed this. This review reflects Aminoscope’s own read of Rx.com’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.

Frequently asked

Is Rx.com really $146 a month?: Only on a six-month plan paid upfront, which is $875 in one charge. Month-to-month semaglutide is $175, and three months is $165/month ($495). Tirzepatide runs $285 month-to-month, $265 across three months and $259 across six ($1,550). To Rx.com's credit the asterisk is right there — "*on a 6-month plan" sits under the headline figure on the homepage, and the full table is on the weight-loss page — so this is a criticism of which number leads, not of the disclosure behind it.
Does Rx.com actually offer TRT, hair loss or women's health treatment?: Not in any way you can use. Its homepage advertises testosterone therapy, dermatology, hair regrowth, women's health and primary care with "Get started" buttons, and every one of those buttons takes you straight back to the homepage. None of the nine such buttons leads to a service, an intake or a third party. The only working program on the site is weight loss.
Is the ED page Rx.com's own service?: No. It is a comparison page. Its "top pick" is QUAD by MEDVi at $114/month, with Hims and Peter MD listed beneath — all three are separate companies we cover independently — and all three of its "Get started" buttons lead back to the homepage. If you want ED treatment, go to a provider that prescribes it rather than a page that ranks other providers.
Which pharmacy fills the prescription?: Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650, named in the footer of every page along with the provider network, MD Integrations. That is real disclosure; many sellers describe the pharmacy only as "a partner compounding pharmacy" and never name it. Manifest is the same facility Nex Gen Health Rx names, if you are comparing the two.
How many states does Rx.com serve?: The site answers this two ways. Its homepage banner says "Licensed Providers in all 50 States"; its weight-loss program page says "49 states served," and its plan footnote says "Not available in Alaska." The program-page figure is the specific one and is consistent with the Alaska exclusion, so 49 is the number to work from — but a service should not contradict itself on coverage, and if you are in Alaska the homepage would tell you the wrong thing.
Is Rx.com legit?: Rx.com is a GLP-1 telehealth service you reach through an online questionnaire and an online intake a clinician reviews. The medications it names are Compounded semaglutide and Compounded tirzepatide. Its stated availability: 49 states (not Alaska) — the homepage says all 50. What it publishes up front: Semaglutide $175/mo month-to-month ($146 on 6 months); tirzepatide $285 ($259). Manifest Pharmacy named. It is cash-pay and states it does not bill insurance. It shows a LegitScript seal. Ask the company for its certificate number before you rely on it. Those are the provider's own published claims rather than checks we could run ourselves, so get the ones that matter to you confirmed in writing before you pay.
Is Rx.com expensive compared with other GLP-1 telehealth providers?: Rx.com publishes a starting figure of $175/mo. Across the 110 GLP-1 telehealth providers we review that publish a single monthly figure, those run $49 to $399 with a median of $189, which puts Rx.com below the median, toward the cheaper end. The other 285 GLP-1 telehealth providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.

Check availability →

Or compare every GLP-1 provider.