Enhance MD review
Clinical, lab-guided
A physician-led, lab-guided GLP-1 program with all-inclusive pricing and a real video visit — our editorial pick.
Our verdict
Enhance MD is our editorial pick because it does the things most cash-pay compounding shops skip: lab diagnostics to guide dosing, ongoing physician oversight, a mandatory video visit, and all-inclusive pricing instead of surprise add-ons. It's still compounded, cash-pay GLP-1 — not branded medication — so hold that caveat, but the care wrapped around it is a genuine step up.
Disclosure: Aminoscope is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.
At a glance
- Category
- GLP-1 telehealth
- Access
- From $99/mo
- Medications
- Semaglutide · Tirzepatide
- Insurance
- Cash-pay, no insurance
- Visit
- Async intake
- Updated
- July 2026
Sponsored alternative
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A low-cost entry point into compounded GLP-1 treatment
Check yourEra availability →What it is
Enhance MD is a physician-led weight-management telehealth that pairs compounded GLP-1 and GIP/GLP-1 protocols with lab diagnostics to guide dosing, and offers NAD⁺ options alongside. It's positioned around clinical oversight rather than the bare-script model common in this category.
How it works
This is the heavier, more clinical end of the field: labs inform your dose, a physician oversees the plan on an ongoing basis, and there's a required video visit rather than a one-off questionnaire. That structure asks more of you up front, but it's closer to how obesity medicine is actually meant to be practiced.
Pricing transparency
Enhance MD publishes an entry point of $99/mo and pitches it as all-inclusive — the appeal is no surprise add-ons layered on later. As always, confirm what the all-in figure covers and how it moves at higher maintenance doses during intake.
Branded vs compounded
Compounded semaglutide and tirzepatide. These are compounding-pharmacy products, not the FDA-approved branded drugs, and the two are not therapeutically equivalent — see our compounded-vs-branded explainer.
Pros and watch-outs
What we like
- Lab-guided dosing rather than a flat protocol
- Ongoing physician oversight, not a one-off script
- Mandatory video visit — a real clinical touchpoint
- All-inclusive pricing, published from $99/mo
- NAD⁺ options available alongside the GLP-1
Watch-outs
- Compounded-only — no FDA-approved branded medication
- The required video visit is more effort than an async shop
Best for
People who want lab-guided dosing and ongoing physician oversight, not just a prescription.
Who should look elsewhere
Anyone who wants branded medication, or the fastest possible async cash-pay checkout with no visit.
The evidence behind what Enhance MD prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- What the semaglutide weight-loss trials actually showed
STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.
- SURMOUNT-1 explained: the trial that made tirzepatide the benchmark
The landmark phase 3 trial of tirzepatide for obesity — the design, the up-to-20.9% weight loss, the safety profile, and the limits of what it proved.
How Enhance MD compares
A few alternatives worth a look, depending on what you’re optimizing for.
- HealthRX
Low-cost compounded GLP-1 with overnight shipping and physician review
See HealthRX → - Oak Longevity
Low-cost compounded GLP-1 bundled with a longevity stack
See Oak Longevity → 
FoundPutting insurance benefits toward GLP-1 treatment
See Found →
More GLP-1 telehealth reviews: SnagRxHe & She MDHumeCare+Try AgelessSkinnyRxPeter MD
Access & cost · Reviewed and last verified July 2026
How we assessed this. This review reflects Aminoscope’s own read of Enhance MD’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- Does Enhance MD require a video visit?
- Yes — Enhance MD includes a mandatory video visit, which is more hands-on than the async, questionnaire-only model many compounded-GLP-1 shops use. Pairing that with lab diagnostics is a large part of why it's our editorial pick.
- Is Enhance MD's pricing really all-inclusive?
- Enhance MD publishes an entry point of $99/mo and positions its pricing as all-inclusive, which is meant to avoid the surprise add-ons some competitors tack on. Confirm exactly what's bundled and how the price changes at higher doses during intake.
- Does Enhance MD offer branded or compounded GLP-1?
- Compounded semaglutide and tirzepatide. These are compounding-pharmacy products, not the FDA-approved branded medications, so they aren't therapeutically equivalent even though the care model around them is unusually thorough.
- Is Enhance MD legit?
- Enhance MD is a GLP-1 telehealth service you reach through an online intake a clinician reviews. The medications it names are Semaglutide and Tirzepatide. What it publishes up front: From $99/mo. It is cash-pay and states it does not bill insurance. What our record does not establish: which states it serves. Ask for those in writing before you pay.
- Is Enhance MD expensive compared with other GLP-1 telehealth providers?
- Enhance MD publishes a starting figure of $99/mo. Across the 42 GLP-1 telehealth providers we review that publish a single monthly figure, those run $49 to $269 with a median of $179, which puts Enhance MD below the median, toward the cheaper end. The other 31 GLP-1 telehealth providers we review quote only after an intake or price by dose, so they are not in that comparison. A starting figure is not a bill — labs, consultations and shipping are often charged separately, so confirm what your own quote includes.