MadeMed review
Flat dosing, quarterly billing
One flat price at every dose, injectable semaglutide at $239 a month billed quarterly, and injectables offered in only 23 named states. There is no month-to-month plan.
Our verdict
MadeMed has thought hard about the incentive under the price. Its own FAQ says the reason it charges one flat rate at every dose is that most telehealth services charge more as you titrate, which turns each dose increase into a revenue decision the prescriber is standing next to. That is an unusually clear-eyed thing for a seller to write about its own category, and the policy backs it up: the same price at 0.25 mg and at 2.4 mg, dose increases never automatic and never sooner than every four weeks, a seven-day warning email before every charge, and cancellation in one click. Two catches. Billing is quarterly or twice-yearly, with no monthly plan, so injectable semaglutide at $239 a month is a $717 charge every three months. And geography: the injectables are offered in 23 named states, under half the country, while the oral forms reach 40.
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At a glance
- Category
- GLP-1 telehealth
- Access
- Semaglutide $239/mo, tirzepatide $399/mo, billed every 3 months (no monthly plan); same price at every dose
- Medications
- Semaglutide · Tirzepatide
- Insurance
- Cash-pay, no insurance
- Visit
- Async intake
- Availability
- Injectables in 23 named states; oral forms in 40
Partner alternative
Enhance MD
Lab-guided treatment under ongoing physician oversight
Check Enhance MD availability →What it is
A cash-pay telehealth service running four weight-loss products, injectable and oral semaglutide and injectable and oral tirzepatide, alongside sermorelin in injectable and oral form, NAD⁺ as an injection and a nasal spray, and tadalafil for sexual health. It describes itself as connecting patients to board-certified physicians and a US pharmacy, and says it holds LegitScript certification. Plans are billed every three months or every six months; the six-month plan is marked most popular and is cheaper per month, so check which one your checkout has selected before you agree to it.
How it works
A five-minute online questionnaire, review by a board-certified physician within 24 hours, and overnight shipping in temperature-controlled packaging with syringes, alcohol swabs and injection supplies included at no extra cost. The injectables ship one vial every two months. If the physician does not prescribe, you are refunded minus a $39 doctor visit fee. The subscription mechanics are where the service is unusually patient-friendly, and each one is stated as policy rather than implied. You are emailed seven days before every charge with the exact amount and the option to pause, skip or cancel. Canceling is one click from the dashboard with no phone call and no retention queue. Pausing stops billing immediately rather than at the end of the cycle. Support is offered by phone, email or chat, with the service saying explicitly that it does not route you to an AI chatbot. Optional meal plans, recipes, shopping lists and exercise programs are included at no extra charge. It also handles transfers deliberately: if you are already on a GLP-1 elsewhere, MadeMed says you do not need to restart titration — share a recent prescription label or invoice and a physician can continue you at your current dose, typically with medication delivered within five to seven business days.
Pricing transparency
Each product page prints its price at every dose, and the figure is the same at every dose. There is no monthly plan: you pay every three months or every six. Injectable semaglutide is $239 a month on the quarterly plan (billed $717 every three months) or $199 on the six-month plan ($1,194). Injectable tirzepatide is $399 quarterly ($1,197) or $369 on six months ($2,214). The under-the-tongue tablets are $219 or $179 for semaglutide and $299 or $279 for tirzepatide. Sermorelin runs $179 or $169 by injection and $109 or $99 orally, NAD⁺ injection $209 or $199, and NAD⁺ nasal spray $279 or $269. MadeMed states the reasoning for the flat price outright: charging more at higher doses puts the prescriber on the wrong side of the patient's treatment. Every GLP-1 order includes L-carnitine at no extra charge, plus free overnight shipping with all injection supplies. Insurance is not accepted and, unusually, neither are FSA or HSA cards; MadeMed compares its price against a stated $1,000 to $1,400 a month for brand-name medication out of pocket.
Branded vs compounded
Four GLP-1 products, semaglutide and tirzepatide, each as a weekly injection or a daily tablet that dissolves under the tongue, plus injectable and oral sermorelin, NAD⁺ by injection or nasal spray, and tadalafil. The semaglutide dose ladder is published rather than left to the funnel: 0.25 mg for roughly four weeks to build tolerance, then 0.5, 1, 1.7 and up to 2.4 mg, with the service noting that most patients stabilize at 1 mg and only about a fifth need more. Tirzepatide runs from 2.5 mg to 15 mg, and the oral semaglutide tablet from 1 mg to a 6 mg daily maximum. Its eligibility criteria and exclusions are stated too — a BMI of 30 or more, or 27 with a weight-related condition, and not appropriate with a personal or family history of medullary thyroid cancer, MEN 2, or in pregnancy or breastfeeding. It also answers the question most services avoid: weight regain after stopping is common, appetite returns to baseline, and some patients stay on a maintenance dose. Compounded preparations are not FDA-approved and are not therapeutically equivalent to Ozempic, Wegovy, Mounjaro or Zepbound. The sermorelin and NAD⁺ lines carry far less human-outcome evidence than the two GLP-1s and belong in a separate column of your reasoning.
Pros and watch-outs
What we like
- One flat price at every dose from 0.25 mg to 2.4 mg, with the incentive argument for it stated in its own FAQ
- Dose increases are never automatic and typically no sooner than every four weeks, with the patient initiating
- A seven-day warning email before every charge, naming the exact amount, with pause, skip and cancel options
- Cancel in one click from the dashboard; pausing stops billing immediately rather than at the next cycle
- Prints the price at every dose on each product page, and publishes an enumerated state list for each product
- Publishes the full dose ladder, the eligibility criteria and the exclusions
- Says weight regain after stopping is common instead of leaving it out
- L-carnitine included with every semaglutide dose, and free overnight temperature-controlled shipping with all supplies
- Continues switchers at their existing dose rather than forcing a restart of titration
- Human support by phone, email or chat, with an explicit commitment not to route you to a chatbot
Watch-outs
- Availability is narrow for the injectables: 23 named states, under half the country (the oral forms reach 40)
- No monthly plan; the cheapest commitment is a quarterly charge, $717 for injectable semaglutide
- If you are not prescribed, the refund holds back a $39 doctor visit fee
- No pharmacy is named on the public pages
- No insurance, and FSA and HSA cards are not accepted
- Compounded only — no FDA-approved branded option
- Sermorelin and NAD⁺ are sold beside the GLP-1s without the evidence gap being flagged
Best for
People in one of its listed states who want the price to stay flat as the dose climbs, can commit to quarterly billing, and want clean subscription controls and a transfer that does not restart titration.
Who should look elsewhere
Anyone outside its published states, anyone who wants to pay one month at a time, or anyone who needs branded medication, insurance billing or HSA/FSA payment.
The evidence behind what MadeMed prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- What the semaglutide weight-loss trials actually showed
STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.
- Oral semaglutide (Rybelsus): what the PIONEER trials actually showed
A GLP-1 peptide in a pill is hard to pull off. PIONEER 1, 4, and 6 plus OASIS 1 — read straight from the primary literature.
- Sermorelin benefits: does it work? What the trials show
A real GHRH drug, read against the anti-aging pitch: an approved growth-hormone-releasing analog with a pediatric track record, and a longevity case built more on biomarkers than outcomes.
- NAD⁺ nasal spray: the delivery format with the least direct evidence
Intranasal NAD⁺ is convenient and heavily marketed, but no human trial shows the spray raises systemic or brain NAD⁺. A straight comparison with the better-studied routes.
How MadeMed compares
A few alternatives worth a look, depending on what you’re optimizing for.
ShedA wide range of GLP-1 formats (injection, drops, lozenges, microdose)
See Shed →
Live VitalPairing a GLP-1 with a wider peptide and longevity protocol
See Live Vital →
Telos RXChoice of GLP-1 formats, including needle-free sublingual tirzepatide
See Telos RX →
More GLP-1 telehealth reviews: Call-On-DocCandor RxCenter for Medical Weight Loss (CMWL)Better Med SpaBeyondMDBiltRx
Access & cost
How we assessed this. This review reflects Aminoscope’s own read of MadeMed’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- Where is MadeMed available?
- It depends on the product. Injectable semaglutide, injectable tirzepatide and both NAD⁺ products are offered in 23 named states: Arizona, Colorado, Connecticut, Delaware, Florida, Georgia, Iowa, Idaho, Illinois, Indiana, Maine, Missouri, Montana, North Dakota, New Mexico, New York, Rhode Island, South Dakota, Texas, Utah, Vermont, Wisconsin and Wyoming. Oral semaglutide, oral tirzepatide and injectable sermorelin are offered in 40 states, excluding Alabama, Alaska, Arkansas, Hawaii, Massachusetts, Missouri, New Mexico, New York, South Carolina and Virginia. Check the page for the exact product before anything else.
- Does the price change as my dose goes up?
- No, and MadeMed explains why in its own words: charging more at higher doses turns every titration conversation into a revenue decision for the prescriber, and it does not want its doctors near that math. The same price applies at 0.25 mg and at 2.4 mg. Dose increases are not automatic either — your dose holds until you say you are ready, and a step up is typically approved no sooner than every four weeks.
- Can I switch to MadeMed without restarting my titration?
- MadeMed says yes. Share your current dose and how long you have been on it during the consult — a recent prescription label or pharmacy invoice helps but is not required — and a physician can continue you at that dose rather than sending you back to 0.25 mg. It says most switchers go from consult to delivered medication in five to seven business days, with priority if you are running low.
- How does MadeMed's billing work?
- Plans are billed every three months or every six months; there is no monthly option. Injectable semaglutide, for example, is $717 every three months or $1,194 every six, and the six-month plan is marked most popular, so check which one is selected at checkout. MadeMed says it emails you seven days before every charge with the exact amount and links to pause, skip or cancel, that cancellation is one click from the dashboard with no phone call, and that pausing stops billing immediately rather than at the end of the cycle. Together, those three policies make the subscription easy to control.
- What does MadeMed offer besides GLP-1?
- Injectable sermorelin ($179 a month quarterly) and oral sermorelin ($109), NAD⁺ as an injection ($209) or a nasal spray ($279), and tadalafil for sexual health, all under the same account. The GLP-1s rest on large published trials; the sermorelin and NAD⁺ lines do not have comparable controlled human-outcome data, so price and judge them separately rather than as part of the same decision.
- Is MadeMed legit?
- MadeMed is a GLP-1 telehealth service you reach through an online intake a clinician reviews. The medications it names are Semaglutide and Tirzepatide. Its stated availability: Injectables in 23 named states; oral forms in 40. What it publishes up front: Semaglutide $239/mo, tirzepatide $399/mo, billed every 3 months (no monthly plan); same price at every dose. It is cash-pay and states it does not bill insurance. Before you pay, ask in writing about a single monthly price you can check before an intake.