PCOS Sisters review
PCOS specialists, membership plus meds
A PCOS-focused telehealth clinic run by nurse practitioners: membership from $99 a month, GLP-1 management from $150, with medication billed by the pharmacy. About a dozen states.
Our verdict
PCOS Sisters is a specialist clinic, not a GLP-1 storefront. Its nurse practitioners treat polycystic ovary syndrome, now also called PMOS, and they use GLP-1s as one tool for the insulin resistance behind it, with attention to dosing, microdosing, B12 levels and keeping weight off afterward. That makes it a strong fit if PCOS is your main concern and you want the same clinician managing your cycles, skin, labs and weight. It is not the cheapest route. GLP-1 care requires a membership of $99 or $129 a month depending on your provider, GLP-1 management is listed from $150 a month, and the medication itself is billed separately by the pharmacy. It also serves only about a dozen states, and the site's own state lists don't fully agree.
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At a glance
- Category
- GLP-1 telehealth
- Access
- Membership $99–$129/mo; GLP-1 management from $150/mo; medication and labs billed separately
- Medications
- Semaglutide · Tirzepatide
- Insurance
- Works with insurance
- Visit
- Video visit
- Availability
- About a dozen states (AZ, CT, FL, GA, IL, NM, NY, OR, TX, UT, VA, WA)
- LegitScript
- Claimed by provider
Partner alternative
yourEra
A low-cost entry point into compounded GLP-1 treatment
Check yourEra availability →What it is
PCOS Sisters Telehealth Clinic & Wellness Center is headquartered in St. Petersburg, Florida, and operates through Lynsey Johnson DNP PLLC, doing business as PCOS Sister Healthcare in Texas, and PCOS Sister Healthcare, PLLC in Illinois and Washington. Its founder, Dr. Lynsey Johnson, is a doctor of nursing practice and family nurse practitioner, and its clinicians are board-certified nurse practitioners, several of whom have PCOS themselves. Nurse practitioners practice independently in Florida and New York and under physician supervision in Georgia and Texas. Besides weight, it treats irregular periods, infertility, acne, unwanted hair, hair thinning and mental health, and offers primary care. Its pricing widget assigns one provider to Arizona, Connecticut, Florida, New Mexico, Texas, Utah and Virginia and the founder to Georgia, Illinois, New York, Oregon and Washington; its service-area page and FAQ each list a slightly different set. It displays a LegitScript seal.
How it works
You can start with a free ten-minute phone call or go straight to booking. A one-time 30-minute evaluation visit costs $75, but GLP-1 prescriptions require an active membership, which includes the evaluation. After you pick your provider and pay, you book a video visit, usually the same week. You must be physically in a state where your provider is licensed at the time of the visit; if you aren't, the visit is canceled and a $25 no-show fee applies. Before visits you upload ID and weigh yourself, and your provider orders labs and imaging as needed. Members get unlimited 30-minute video visits and messages with their nurse practitioner, a personalized diet and exercise plan through the PCOS Sisters Fitness app, and a private peer community. GLP-1 plans can include microdosing, oral options, combinations to protect B12 levels, and a maintenance plan for after the medication. Controlled substances aren't prescribed.
Pricing transparency
Membership is billed monthly at $99 with one provider or $129 with the founder; prepaid plans are offered at a discount. GLP-1 management is listed at "$150* per month" with membership required, and the clinic's FAQ says GLP-1 prescriptions start at $150 a month; the site doesn't spell out how that figure combines with the membership fee, so ask before you join. What is clear is that labs, imaging and medications are not included: they're billed by the lab, imaging center or pharmacy. A basic discounted PCOS lab panel runs about $335. Insurance is limited. The clinic accepts Aetna and UnitedHealthcare for evaluation visits in Georgia, and an insured-patient subscription of $50 a month is offered with Aetna and UnitedHealthcare in Georgia and Blue Cross Blue Shield and UnitedHealthcare in Texas, separate from your insurance costs. Insurance doesn't cover membership, but you can use it for labs, imaging and medication. Medicare and Medicaid aren't accepted. Refund terms aren't described on the pages read.
Branded vs compounded
Semaglutide, which the clinic describes by its brand-name equivalents Wegovy and Ozempic, tirzepatide, oral GLP-1 options, and metformin and other insulin-targeted medicines, chosen around your PCOS profile. The site doesn't say whether its GLP-1s are compounded or brand-name; it names two partner pharmacies, Strive Pharmacy in Gilbert, Arizona and Striker Pharmacy in Katy, Texas, and you can ask which product and pharmacy your prescription would use. Compounded drugs are not FDA-approved. The clinic notes that semaglutide was added to updated PCOS treatment guidance in 2023 for its effect on insulin resistance, and the clinic presented early results from its own weight-loss program in 2025, which it describes as a chart review not yet published. A search of the FDA warning-letter database for PCOS Sisters and its operating companies returned no letters.
Pros and watch-outs
What we like
- Nurse practitioners who specialize in PCOS, many with PCOS themselves
- Unlimited video visits and messaging with your own clinician
- Microdosing, oral options and long-term maintenance planning
- Fitness app, diet plan and peer community included
- Some insurance accepted in Georgia and Texas; displays a LegitScript seal
Watch-outs
- Membership, GLP-1 management and medication are separate costs
- Unclear how the $150 GLP-1 fee adds to the membership
- Only about a dozen states, and its state lists disagree
- Doesn't say whether its GLP-1s are compounded
- No Medicare or Medicaid; refund terms not published
Best for
Women with PCOS in a served state who want GLP-1 treatment managed by PCOS specialists alongside cycle, skin, fertility and metabolic care.
Who should look elsewhere
Anyone who just wants the lowest all-in GLP-1 price, lives outside its states, or is on Medicare or Medicaid.
The evidence behind what PCOS Sisters prescribes
We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.
- Semaglutide and GLP-1s for PCOS: what the evidence actually shows
PCOS runs on insulin resistance and weight — exactly what GLP-1s improve. A straight read of the RCTs and meta-analyses, the off-label reality, and the fertility caveat.
- “Microdosing” GLP-1 drugs: a trend, not a protocol — what the evidence says
Sub-therapeutic semaglutide and tirzepatide is spreading fast. The pharmacology is clear, the honest part is clearer: efficacy is dose-related, and no trial has tested intentional microdosing.
- Tirzepatide vs semaglutide for weight loss: what the trials actually support
Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.
How PCOS Sisters compares
A few alternatives worth a look, depending on what you’re optimizing for.
EdenCompounded or branded GLP-1 through one consumer telehealth account
See Eden →
WellMedRxCompounded tirzepatide with a named clinician network and pharmacy
See WellMedRx →
NuBloomWomen in midlife who want a month-to-month compounded GLP-1 with optional coaching and hormone care from the same practice
See NuBloom →
More GLP-1 telehealth reviews: Avono HealthBalanced Hormone HealthBasalBelleEnhance MDHealthRX
Pharmacology & mechanisms
How we assessed this. This review reflects Aminoscope’s own read of PCOS Sisters’s publicly-stated model — pricing transparency, clinical oversight, medication clarity, and access — against our editorial methodology. We publish no fabricated ratings or first-hand outcomes. A partnership never changes the assessment — see how we make money.
Frequently asked
- How much does PCOS Sisters cost for GLP-1s?
- A membership is required, at $99 or $129 a month depending on your provider. GLP-1 management is listed from $150 a month, and the medication itself is billed separately by the pharmacy. Ask how the fees combine before you join.
- What states does PCOS Sisters serve?
- Its provider pricing lists Arizona, Connecticut, Florida, Georgia, Illinois, New Mexico, New York, Oregon, Texas, Utah, Virginia and Washington. Its service-area page and FAQ each show a slightly different list, so confirm your state when you book.
- Does PCOS Sisters take insurance?
- Partly. It accepts Aetna and UnitedHealthcare for visits in Georgia and offers an insured-patient subscription with some plans in Georgia and Texas. Membership isn't covered, but you can use insurance for labs, imaging and medication. Medicare and Medicaid aren't accepted.
- Does PCOS Sisters offer oral GLP-1s?
- Yes, oral GLP-1 options may be available for patients who prefer to avoid injections or respond strongly to low doses, along with microdosing and combination plans. Your provider decides what fits.
- Is PCOS Sisters legit?
- PCOS Sisters is a GLP-1 telehealth service you reach through a video visit with a clinician. The medications it names are Semaglutide and Tirzepatide. Its stated availability: About a dozen states (AZ, CT, FL, GA, IL, NM, NY, OR, TX, UT, VA, WA). What it publishes up front: Membership $99–$129/mo; GLP-1 management from $150/mo; medication and labs billed separately. It states it works with insurance. It shows a LegitScript seal. Ask the company for its certificate number before you rely on it. Before you pay, ask in writing about a single monthly price you can check before an intake.