Zera Health review

What it is

Zera Health is a telehealth platform that describes itself as a technology company rather than a medical practice: independent licensed physicians, nurse practitioners and physician assistants make the prescribing decisions, and the platform handles intake, billing and support. Its terms name TelegraMD as the telehealth platform behind its care and Strive Pharmacy, a licensed 503A compounding pharmacy, as the pharmacy that dispenses all of its compounded medication. Beyond weight loss it sells NAD⁺ as an injection or nasal spray, sermorelin, MIC with B12 injections, hormone therapy for women, testosterone and erectile-dysfunction treatment for men, and hair-loss products. Support runs by phone and email from a Florida number, and its telehealth notice is governed by Florida law. The site doesn't give a corporate name or street address, and it says it has treated more than 5,000 patients. It displays a LegitScript badge image, though the badge isn't linked to LegitScript's verification page.

How it works

You complete a short online health assessment, which Zera says takes about two minutes and needs no appointment. A licensed provider reviews it and, if appropriate, writes a personalized plan; approvals are often same day. The prescription goes to Strive Pharmacy, which ships it free in discreet cold-chain packaging; Zera quotes 48 to 72 hours after approval on one page and five to seven business days for a first shipment on another. After that, you message your provider through the patient portal, which is also where you'll find your provider's name and credentials after the first consultation; non-urgent messages may wait until the next business day. Dose changes are handled through the portal without changing your price. The site doesn't describe routine scheduled check-ins, so plan to reach out yourself when you're ready to step up a dose or if side effects are a problem.

Pricing transparency

Prices on the semaglutide page are $179 a month on the monthly plan or $149 a month billed every three months, and on the tirzepatide page $255 a month or $215 a month billed quarterly. Zera says the price is the same at every dose and includes provider care, medication and free shipping, with no insurance needed. During a sale running to November 1, the first month is advertised at $149 for semaglutide and $199 for tirzepatide, shown against regular first-month prices of $249 and $315. The oral tablet is listed from $169 and the microdose plan from $129 for the first month, but their pages repeat the semaglutide plan cards, so check the real recurring price before you buy. You're charged for the first month when you finish the intake, and refunded in full if a provider disqualifies you. Otherwise there are no refunds once a prescription has gone to the pharmacy and no prorated refunds within a billing cycle. Cancel by email, phone or portal chat at least 72 hours before your billing date, or you'll be charged one more cycle.

Branded vs compounded

Compounded semaglutide and compounded tirzepatide as weekly injections, a compounded semaglutide dissolving tablet taken daily, and a lower-dose microdose injection plan. All are prepared by Strive Pharmacy for the individual patient. Compounded drugs are not FDA-approved, and Zera's own disclaimers say so; it also says it doesn't supply brand-name Wegovy, Ozempic, Mounjaro or Zepbound. The site describes its medication as third-party lab tested but doesn't publish the testing. If you want a brand-name drug or need insurance billing, look elsewhere. A search of the FDA warning-letter database for Zera Health returned no letters.

Pros and watch-outs

The evidence behind what Zera Health prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• What the semaglutide weight-loss trials actually showed

  STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.

• Tirzepatide vs semaglutide for weight loss: what the trials actually support

  Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.

• “Microdosing” GLP-1 drugs: a trend, not a protocol — what the evidence says

  Sub-therapeutic semaglutide and tirzepatide is spreading fast. The pharmacology is clear, the honest part is clearer: efficacy is dose-related, and no trial has tested intentional microdosing.

• Compounded vs branded GLP-1: regulatory status, sourcing and the evidence

  Compounded GLP-1 isn't FDA-approved, the shortage exception behind it ended in 2025, the FDA moved against mass-marketed copies in 2026, and the trial data belong to the branded product. Here's the precise picture.

How Zera Health compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Gala Health

  A guided, program-style GLP-1 weight-care experience

  See Gala Health →
• Direct Meds

  Straightforward compounded GLP-1 without an insurance requirement

  See Direct Meds →
• Ondra Health

  Cash-pay buyers who want a low month-to-month compounded price, a choice of named pharmacies and the same price at every dose

  See Ondra Health →

More GLP-1 telehealth reviews: VivioMD · Walgreens Weight Management · Potere Health MD · Primary Clinic · Recovery Delivered · Revive Meds