Alloy review

What it is

Alloy is a telehealth company for women at midlife, mainly known for menopause hormone therapy, with treatments for skin, sexual health, hair and gut health alongside its weight program. Its terms name Alloy Health, Inc. and say Alloy is not a medical group: consultations come from independent U.S.-licensed physicians, which it describes as board-certified menopause specialists who follow guidance from ACOG and The Menopause Society. Compounded and other mail-order prescriptions go through three pharmacies its terms name: Curexa Pharmacy in New Jersey, BLEND Pharmacy in Ohio and Gogo Pharmacy in Kentucky. Brand-name Wegovy is filled by NovoCare and Zepbound by LillyDirect, the manufacturers' own pharmacies. Support is by email or text, from 8 a.m. to 8 p.m. Eastern on weekdays and 10 a.m. to 7 p.m. on weekends. Weight Care is offered in most states, with brand-name drugs only in Alabama, Arkansas, California, Nevada and D.C., and no weight care in Louisiana or Mississippi. The site displays a LegitScript seal.

How it works

You fill out an online intake about your health, symptoms and goals, which takes five to ten minutes, and a doctor reviews it and sends a plan, usually within 12 hours. If a compounded drug is prescribed, it ships free to your door; if a brand-name drug is prescribed, the doctor sends it to NovoCare or LillyDirect, which sends you a link to pay and then ships it. From there, the Weight Care fee covers unlimited messaging with your doctor, refills, renewals and dose adjustments through titration and maintenance, side-effect management, and nutrition and exercise guidance aimed at midlife. Personalized dosing, including gentler starts and microdosing, is available. If you also take menopause hormone therapy, the same doctor can coordinate the two, and you can switch between medications through the program as your needs change.

Pricing transparency

Weight Care is $99 a month, and medication is extra. Compounded semaglutide starts at $70 for a one-month supply, compounded tirzepatide at $100, and compounded liraglutide, a daily injection, at $115. Brand-name prices are listed from $299 a month for Zepbound or the Zepbound KwikPen, from $199 for the Wegovy pen, and from $149 for the Wegovy pill or Foundayo; the brand-name drugs are paid to the manufacturer's pharmacy. So the lowest monthly total is $169 with compounded semaglutide. New customers get $50 off the first month of Weight Care with a code. The subscription renews automatically, and to stop it you cancel at least seven days before the end of the billing period, by email or from your dashboard. Membership and consultation fees are non-refundable; refund requests for physical products must be made within 30 days of delivery, and drugs bought from a manufacturer's pharmacy aren't refundable through Alloy. It doesn't take insurance, but it gives receipts you can submit for HSA, FSA or out-of-network reimbursement.

Branded vs compounded

Alloy offers one of the widest GLP-1 menus around. Brand-name Wegovy and Zepbound are FDA-approved for weight management, and so are the Wegovy pill and Foundayo, both daily tablets. Compounded semaglutide, tirzepatide and liraglutide are prepared by licensed compounding pharmacies for individual patients, and Alloy's disclosures say clearly that compounded drugs are not FDA-approved or reviewed for safety, effectiveness or quality. The average weight-loss figures on its pages, about 15% for Wegovy and up to 20% for Zepbound, come from the branded drugs. Compounded and microdosed options aren't available in Alabama, Arkansas, California, Nevada or D.C. A search of the FDA warning-letter database under Alloy and its site name returned no letters to the company.

Pros and watch-outs

The evidence behind what Alloy prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• What the semaglutide weight-loss trials actually showed

  STEP 1, STEP 4, and SELECT — the efficacy, the rebound, and the cardiovascular signal, read straight from the primary literature.

• Tirzepatide vs semaglutide for weight loss: what the trials actually support

  Most comparisons are cross-trial. Only SURPASS-2 and SURMOUNT-5 randomized one drug against the other — here's the precise distinction.

• Liraglutide (Saxenda, Victoza): the first-gen daily GLP-1, read from the trials

  About 8% weight loss in SCALE, a real cardiovascular benefit in LEADER, and a daily needle — the honest baseline that weekly semaglutide and tirzepatide now eclipse.

• GLP-1 pill vs injection: what you trade for swallowing it

  Oral semaglutide 50 mg matched the injection to within 0.2 of a percentage point — but not at the approved dose, and the daily fasting protocol is the cost nobody mentions.

How Alloy compares

A few alternatives worth a look, depending on what you’re optimizing for.

• Live Vital

  Pairing a GLP-1 with a wider peptide and longevity protocol

  See Live Vital →
• Trimi Health

  Low-cost compounded GLP-1 with thorough dosing guidance

  See Trimi Health →
• Midi Health

  Women in perimenopause or menopause who want weight care, and possibly hormone therapy, from one clinician, with insurance paying for the visits

  See Midi Health →

More GLP-1 telehealth reviews: FeelGood · RxSpan MD · Telos RX · Ro · Hims · Henry Meds