StackMD review

What it is

StackMD (Medical 360 HC PLLC, a New York limited liability company) is a WooCommerce storefront selling compounded medication across several verticals: GLP-1 weight loss, peptides and longevity, men's health, sexual health, brain health and skin care. Its peptide and longevity shelf carries sermorelin at $175 to $525, NAD⁺ injections at $160 to $480 as a multi-dose vial at 100 mg/mL in 10 mL, and glutathione. Its terms describe it as a technology, marketing and administrative platform rather than the clinical provider, with telehealth consultations provided by SamaritanMD.

How it works

Storefront-first, with the clinical layer explicitly separated and — unusually — named. Its terms state that StackMD operates as a technology, marketing and administrative platform, and its refund policy states that telehealth consultations are provided by SamaritanMD, that charges appear on your statement from SamaritanMD rather than from StackMD, and that StackMD has no authority to issue refunds or resolve billing disputes on SamaritanMD's behalf. Naming the clinical partner is a real positive; the split responsibility it creates is a real negative, because it means the entity you buy from is not the entity you would have to argue with. Availability is stated in the terms themselves rather than only in marketing — telehealth available in all fifty states, with care delivered by providers licensed in the patient's state — though the site hedges that availability of specific treatments may still vary. The compounding pharmacy is never named, described only as a licensed third party. Its terms impose binding arbitration in New York with jury-trial and class-action waivers, and its refund policy opens by stating all sales are final.

Pricing transparency

Transparent on its GLP-1 ladder and not usable on its peptide line, for two separate reasons. First, the billing unit: sermorelin at $175 to $525 and NAD⁺ at $160 to $480 are both sold at checkout as a "4-Week Supply" or a "12-Week Supply". A four-week cycle is thirteen charges in a year, not twelve, so a four-week price is roughly 8% higher annually than the same number labelled monthly — which is precisely the comparison a reader makes when scanning a roundup. Second, the site contradicts itself: its homepage tile advertises NAD⁺ as "Starts @ $140" while the NAD⁺ product page opens at $160. We publish no floor on either board for those two reasons together. The "Plans starting at just $125/month" line that appears in its Why StackMD section belongs to its compounded semaglutide ladder — 1 mg $125, 2 mg $149, 4 mg $175, 6 mg $199, 10 mg $225 — and is not a sermorelin or NAD⁺ price. To its credit, that GLP-1 ladder is published dose by dose rather than as a single "from" figure, which is genuinely rare and which we would like to see applied to the peptide line.

Branded vs compounded

Compounded; not FDA-approved — stated by StackMD itself, in its own words, on every product page: compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, efficacy or quality, and sermorelin specifically is described as a compounded peptide not FDA-approved for general use. That is the correct disclosure and better phrased than most. Prescription required only if a licensed provider finds it appropriate. The compounding pharmacy is not named, and compounded sterile products are not reviewed by the FDA for purity and potency the way approved drugs are. On the evidence, sermorelin is a GHRH analogue acting on a real, well-described growth-hormone axis with thin long-term human outcome data past short-term IGF-1 movement. Injected NAD⁺ has no controlled human outcome trials at all; the forms with human trial data are the oral precursors NR and NMN, which raise a blood NAD⁺ level rather than demonstrate a clinical benefit. Injectable glutathione has essentially no controlled human outcome data behind the skin and detox claims made for it. StackMD's NAD⁺ page is at least specific about what you receive — 100 mg/mL in a 10 mL multi-dose vial, with typical use described as 0.5 to 1 mL up to five times a week as directed — which is more than most services state. Individual results vary.

Pros and watch-outs

The evidence behind what StackMD prescribes

We grade the molecules, not the marketing. Here is what the human data actually shows for each thing on their menu.

• Sermorelin: a real GHRH drug, read against the anti-aging pitch

  An approved growth-hormone-releasing analog with a pediatric track record — and a longevity case built more on biomarkers than outcomes.

• NAD injections: how to get them near you or online, and what the evidence really says

  Subcutaneous NAD+ injections are sold as a cheaper, at-home alternative to the IV drip — via “near me” clinics or telehealth shipped to your door. They’re compounded, not FDA-approved, and have no outcome trials; oral NR/NMN precursors are the route with the human data.

• NAD+ precursors (NR and NMN): what the human trials actually show

  They raise NAD+ and look safe short-term — but human evidence is surrogate-marker level, and no trial shows they extend healthspan.

• Glutathione: the master antioxidant, and where the evidence actually is

  Oral glutathione really does raise your body stores (a 6-month RCT proved it) — but the longevity and detox claims are unproven, skin-lightening is modest, and IV glutathione is the most marketed, least evidenced route. The precursors may be the smarter bet.

How StackMD compares

A few alternatives worth a look, depending on what you’re optimizing for.

• RHRylo Health

  NAD⁺ buyers who want a named pharmacy and the month-to-month rate stated up front

  See Rylo Health →
• SPSpry

  People who want NAD⁺ beside sermorelin on one platform and will read the FDA badge sceptically

  See Spry →
• PEPeptidesRx

  NAD⁺ buyers who want milligrams and concentration stated, not just a monthly fee

  See PeptidesRx →