Is Zepbound better than Wegovy for weight loss?

In SURMOUNT-5, the head-to-head trial, people on Zepbound lost 20.2% of body weight on average at 72 weeks against 13.7% on Wegovy. Tolerability, cost and coverage decide which is right for a given person.

Is Zepbound cheaper than Wegovy without insurance?

At the 2.5 mg starting dose, Lilly's self-pay vial costs less than the standard Wegovy self-pay pen; at 7.5 mg and above it costs more. The short answer at the top of the page has the current figures.

How much more is compounded tirzepatide than compounded semaglutide?

It varies by service. The table shows the difference for every service that publishes both month-to-month prices, from no difference to well over $100 a month.

Can I go from Wegovy to tirzepatide directly?

A prescriber can switch you, but the doses do not convert: Wegovy runs from 0.25 mg to 2.4 mg and tirzepatide from 2.5 mg to 15 mg, so the new drug gets its own starting dose and titration.

Alternatives to Wegovy

Alternatives to Wegovy, and what switching to tirzepatide costs

Wegovy is already approved for weight management, so the reason to look elsewhere is usually cost or results, not the label. The table answers the cost side directly: for each service that prices both molecules, it shows what tirzepatide costs next to semaglutide.

Short answer

Zepbound (tirzepatide) is the approved alternative with the larger average weight loss in a head-to-head trial. Across 47 services that publish month-to-month prices for both compounded molecules, tirzepatide costs a median $70 a month more than semaglutide; 2 charge the same or less. Bought from the manufacturers, the Wegovy pen is $349 a month and Zepbound vials $299 to $449.

By Julian RothResearch & data

47 providers comparedReviewed against our editorial methodologyUpdated August 2026

Disclosure: Aminoscope is reader-supported. Some links below are affiliate links — if you start care through them we may earn a commission, at no extra cost to you. Partners are listed first; a commission never changes what we write about a provider. How we make money.

The shortlist

47 providers, side by side

Included: services that publish a month-to-month price for BOTH compounded semaglutide and compounded tirzepatide, so the switch can be priced at one service. The Access cell gives both figures and the difference. Partners are listed first; within each group, the smallest tirzepatide premium comes first.

Sort

Provider	Access	Medications	Insurance	Visit	Go
CollectivePartner Low price, membership required Read review →	Tirzepatide $69 vs semaglutide $59: +$10 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Strut HealthPartner One-stop telehealth Read review →	Tirzepatide $149 vs semaglutide $129: +$20 a month to switch	SemaglutideTirzepatide+1	Cash-pay	Async	Check availability
Bodybuilding Health+Partner Fitness-oriented Read review →	Tirzepatide $209 vs semaglutide $179: +$30 a month to switch	SemaglutideTirzepatide	Cash-pay	Async	Check availability
HealthRXPartner Low-cost, overnight Read review →	Tirzepatide $214 vs semaglutide $165: +$49 a month to switch	SemaglutideTirzepatide	Cash-pay	Async	Check availability
CoreAge RxPartner Flat dosing price, vague sourcing Read review →	Tirzepatide $149 vs semaglutide $99: +$50 a month to switch	SemaglutideTirzepatide	Cash-pay	—	Check availability
SnagRxPartner Names its pharmacies Read review →	Tirzepatide $149 vs semaglutide $99: +$50 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	—	Check availability
FoundPartner Insurance-friendly Read review →	Tirzepatide $359 vs semaglutide $289: +$70 a month to switch	SemaglutideTirzepatide+1	Insurance	VideoAsync	Check availability
yourEraPartner Same price every dose Read review →	Tirzepatide $159 vs semaglutide $79: +$80 a month to switch	SemaglutideTirzepatide	Cash-pay	Async	Check availability
HumeCare+Partner Lean-mass tracking, price behind a quiz Read review →	Tirzepatide $379 vs semaglutide $279: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
WillowPartner Prices every dose Read review →	Tirzepatide $399 vs semaglutide $299: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide+1	Cash-pay	QuizAsync	Check availability
Direct MedsPartner Simple cash-pay Read review →	Tirzepatide $399 vs semaglutide $297: +$102 a month to switch	SemaglutideTirzepatide+1	Cash-pay	Async	Check availability
Sprout Health Named pharmacies Read review →	Tirzepatide $199 vs semaglutide $149: +$50 a month to switch	SemaglutideTirzepatide	Cash-pay	QuizAsyncVideo	Check availability
Vyvron One program price, per 4 weeks Read review →	Tirzepatide $249 vs semaglutide $249: no extra cost to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Lighter You Coaching included, starting prices only Read review →	Tirzepatide $169 vs semaglutide $169: no extra cost to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Nova All-in price quoted Read review →	Tirzepatide $210 vs semaglutide $198: +$12 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Bayan Health Low entry, broad menu Read review →	Tirzepatide $149 vs semaglutide $129: +$20 a month to switch	Compounded semaglutideCompounded tirzepatide+1	Cash-pay	QuizAsync	Check availability
NEUVÉ Health Every route priced Read review →	Tirzepatide $160 vs semaglutide $138: +$22 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizVideo	Check availability
Mochi Health Titration-focused Read review →	Tirzepatide $90 vs semaglutide $60: +$30 a month to switch	SemaglutideTirzepatide+2	Insurance	Video	Check availability
Mondae Headline matches checkout Read review →	Tirzepatide $126 vs semaglutide $87: +$39 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Trellis Vitality Flat price at every dose Read review →	Tirzepatide $199 vs semaglutide $150: +$49 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Nex Gen Health Rx Banner and catalog disagree Read review →	Tirzepatide $239 vs semaglutide $190: +$49 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizVideo	Check availability
RENN Health One bill, operator unnamed Read review →	Tirzepatide $199 vs semaglutide $149: +$50 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Science & Co Cheap on a 12-month tie Read review →	Tirzepatide $199 vs semaglutide $149: +$50 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
RX Bella Banner $199, catalog $249 Read review →	Tirzepatide $299 vs semaglutide $249: +$50 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Trimi Health Flat price, deep guides Read review →	Tirzepatide $235 vs semaglutide $175: +$60 a month to switch	SemaglutideTirzepatide	Cash-pay	Async	Check availability
Glam Health Headline price misleads Read review →	Tirzepatide $310 vs semaglutide $250: +$60 a month to switch	Compounded tirzepatide + B12Compounded semaglutide + B12	Cash-pay	QuizAsync	Check availability
FORM Named pharmacy, many plan types Read review →	Tirzepatide $219 vs semaglutide $159: +$60 a month to switch	Compounded semaglutideCompounded tirzepatide+2	Cash-pay	QuizAsync	Check availability
Edessa Tabled plainly, pharmacy unnamed Read review →	Tirzepatide $239 vs semaglutide $179: +$60 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
EdgeRx Compounded, flat monthly pricing Read review →	Tirzepatide $299 vs semaglutide $229: +$70 a month to switch	Compounded semaglutide + glycine/B12Compounded tirzepatide + glycine/B12	Cash-pay	QuizAsync	Check availability
Rehydra+ Wellness Priced by dose; memberships lock 6 months Read review →	Tirzepatide $219 vs semaglutide $149: +$70 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
No BS RX Monthly price is the headline Read review →	Tirzepatide $249 vs semaglutide $179: +$70 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Renlo Health Flat price, backend named Read review →	Tirzepatide $269 vs semaglutide $199: +$70 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Nolu Flat price per dose, named pharmacies Read review →	Tirzepatide $279 vs semaglutide $199: +$80 a month to switch	Compounded semaglutideCompounded tirzepatide+1	Cash-pay	QuizAsync	Check availability
AurenRx Flat price, named pharmacy Read review →	Tirzepatide $259 vs semaglutide $179: +$80 a month to switch	Compounded semaglutide + glycine/B12Compounded tirzepatide + glycine/B12	Cash-pay	QuizAsync	Check availability
Magnolia Regenerative Medicine Cheap, pharmacy unnamed Read review →	Tirzepatide $179 vs semaglutide $99: +$80 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Idgie Health Pharmacy named, plans shown Read review →	Tirzepatide $229 vs semaglutide $149: +$80 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
He & She MD Flat dosing, prepay headline Read review →	Tirzepatide $339 vs semaglutide $249: +$90 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Prime Doctor RX Both prices on the card Read review →	Tirzepatide $339 vs semaglutide $249: +$90 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
the edit. Fully disclosed care chain Read review →	Tirzepatide $309 vs semaglutide $209: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Pepti Priced at every dose Read review →	Tirzepatide $199 vs semaglutide $99: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Pallas Health Flat dose pricing, named pharmacies Read review →	Tirzepatide $299 vs semaglutide $199: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide+1	Cash-pay	QuizAsync	Check availability
AHBARx Honest prepay arithmetic Read review →	Tirzepatide $349 vs semaglutide $249: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Andrew Meds Prepay ladder, fully shown Read review →	Tirzepatide $299 vs semaglutide $199: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsyncVideo	Check availability
Oria Meds Pharmacy named with address Read review →	Tirzepatide $249 vs semaglutide $149: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
SexyMD Headline is the 48-week rate Read review →	Tirzepatide $369 vs semaglutide $269: +$100 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Rx.com Weight loss only, well documented Read review →	Tirzepatide $285 vs semaglutide $175: +$110 a month to switch	Compounded semaglutideCompounded tirzepatide	Cash-pay	QuizAsync	Check availability
Breeze Meds Names its pharmacy Read review →	Tirzepatide $399 vs semaglutide $199: +$200 a month to switch	SemaglutideTirzepatide+1	Cash-pay	Async	Check availability

CollectivePartnerLow price, membership required
A low all-in GLP-1 cost, if you will actually keep the annual membership
Access
Tirzepatide $69 vs semaglutide $59: +$10 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Strut HealthPartnerOne-stop telehealth
A general telehealth that covers GLP-1 alongside other everyday care
Access
Tirzepatide $149 vs semaglutide $129: +$20 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatideOral
Visit
Async
Check availability
Bodybuilding Health+PartnerFitness-oriented
GLP-1 alongside NAD⁺ and sermorelin from a fitness brand
Access
Tirzepatide $209 vs semaglutide $179: +$30 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatide
Visit
Async
Check availability
HealthRXPartnerLow-cost, overnight
Low-cost compounded GLP-1 with overnight shipping and physician review
Access
Tirzepatide $214 vs semaglutide $165: +$49 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatide
Visit
Async
Check availability
CoreAge RxPartnerFlat dosing price, vague sourcing
Flat pricing that does not climb as your dose titrates up
Access
Tirzepatide $149 vs semaglutide $99: +$50 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatide
Visit
—
Check availability
SnagRxPartnerNames its pharmacies
Naming the pharmacies that actually fill the prescription
Access
Tirzepatide $149 vs semaglutide $99: +$50 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
—
Check availability
FoundPartnerInsurance-friendly
Compounded GLP-1 with the drug included, and insurance for the visits
Access
Tirzepatide $359 vs semaglutide $289: +$70 a month to switch
Insurance
Insurance
Medications
SemaglutideTirzepatideBranded
Visit
VideoAsync
Check availability
yourEraPartnerSame price every dose
A low-cost entry point into compounded GLP-1 treatment
Access
Tirzepatide $159 vs semaglutide $79: +$80 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatide
Visit
Async
Check availability
HumeCare+PartnerLean-mass tracking, price behind a quiz
Tracking lean mass rather than scale weight, if you read the guarantee terms first
Access
Tirzepatide $379 vs semaglutide $279: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
WillowPartnerPrices every dose
Buyers who want every dose priced and the pharmacies named, and will pay more for it
Access
Tirzepatide $399 vs semaglutide $299: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatideOral
Visit
QuizAsync
Check availability
Direct MedsPartnerSimple cash-pay
Straightforward compounded GLP-1 without an insurance requirement
Access
Tirzepatide $399 vs semaglutide $297: +$102 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatideOral
Visit
Async
Check availability
Sprout HealthNamed pharmacies
Compounded GLP-1 with named-pharmacy and LegitScript transparency
Access
Tirzepatide $199 vs semaglutide $149: +$50 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatide
Visit
QuizAsyncVideo
Check availability
VyvronOne program price, per 4 weeks
Buyers who want one flat GLP-1 program price from a service that names its clinical partner and pharmacies
Access
Tirzepatide $249 vs semaglutide $249: no extra cost to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Lighter YouCoaching included, starting prices only
Buyers who want dietitian visits and coaching bundled into a GLP-1 plan
Access
Tirzepatide $169 vs semaglutide $169: no extra cost to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
NovaAll-in price quoted
Readers who want the membership included in the quoted price rather than added at checkout
Access
Tirzepatide $210 vs semaglutide $198: +$12 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Bayan HealthLow entry, broad menu
Readers who want a microdose entry point and their lab work priced in the same catalog
Access
Tirzepatide $149 vs semaglutide $129: +$20 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatideRetatrutide / orforglipron / cagrilintide
Visit
QuizAsync
Check availability
NEUVÉ HealthEvery route priced
Readers comparing injection against sublingual, and microdose against standard, on price
Access
Tirzepatide $160 vs semaglutide $138: +$22 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizVideo
Check availability
Mochi HealthTitration-focused
A clinician-led, titration-focused program
Access
Tirzepatide $90 vs semaglutide $60: +$30 a month to switch
Insurance
Insurance
Medications
SemaglutideTirzepatideOral+1
Visit
Video
Check availability
MondaeHeadline matches checkout
Buyers who want a low, honest month-to-month price with the compounding source named
Access
Tirzepatide $126 vs semaglutide $87: +$39 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Trellis VitalityFlat price at every dose
Buyers who want one flat GLP-1 price at every dose, from a named pharmacy
Access
Tirzepatide $199 vs semaglutide $150: +$49 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Nex Gen Health RxBanner and catalog disagree
Buyers who want the 503A pharmacy named and the prepay total shown, not a monthly average
Access
Tirzepatide $239 vs semaglutide $190: +$49 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizVideo
Check availability
RENN HealthOne bill, operator unnamed
One subscription and one care team across GLP-1, NAD+ and testosterone
Access
Tirzepatide $199 vs semaglutide $149: +$50 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Science & CoCheap on a 12-month tie
A low GLP-1 rate if a twelve-month commitment is realistic for you
Access
Tirzepatide $199 vs semaglutide $149: +$50 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
RX BellaBanner $199, catalog $249
Readers who want GLP-1, NAD⁺ and peptides from one brand and will price it from the catalog, not the banner
Access
Tirzepatide $299 vs semaglutide $249: +$50 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Trimi HealthFlat price, deep guides
Low-cost compounded GLP-1 with thorough dosing guidance
Access
Tirzepatide $235 vs semaglutide $175: +$60 a month to switch
Insurance
Cash-pay
Medications
SemaglutideTirzepatide
Visit
Async
Check availability
Glam HealthHeadline price misleads
Compounded tirzepatide or semaglutide with a home injection kit
Access
Tirzepatide $310 vs semaglutide $250: +$60 a month to switch
Insurance
Cash-pay
Medications
Compounded tirzepatide + B12Compounded semaglutide + B12
Visit
QuizAsync
Check availability
FORMNamed pharmacy, many plan types
Comparing compounded and branded GLP-1 options in one place
Access
Tirzepatide $219 vs semaglutide $159: +$60 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatideWegovy (semaglutide)+1
Visit
QuizAsync
Check availability
EdessaTabled plainly, pharmacy unnamed
Buyers who want a short, tabled GLP-1 price list and the clinician network named
Access
Tirzepatide $239 vs semaglutide $179: +$60 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
EdgeRxCompounded, flat monthly pricing
Men already using EdgeRx's other peptide protocols who want GLP-1 folded into the same subscription
Access
Tirzepatide $299 vs semaglutide $229: +$70 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutide + glycine/B12Compounded tirzepatide + glycine/B12
Visit
QuizAsync
Check availability
Rehydra+ WellnessPriced by dose; memberships lock 6 months
Buyers who want dose-by-dose GLP-1 prices and a call with a provider before committing
Access
Tirzepatide $219 vs semaglutide $149: +$70 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
No BS RXMonthly price is the headline
Readers who want the month-to-month price first and every plan length beside it
Access
Tirzepatide $249 vs semaglutide $179: +$70 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Renlo HealthFlat price, backend named
A flat monthly GLP-1 price with the provider group, pharmacy and 503A basis all named
Access
Tirzepatide $269 vs semaglutide $199: +$70 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
NoluFlat price per dose, named pharmacies
Compounded GLP-1 injections or a daily oral pill
Access
Tirzepatide $279 vs semaglutide $199: +$80 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatideCompounded oral semaglutide
Visit
QuizAsync
Check availability
AurenRxFlat price, named pharmacy
Buyers who want flat monthly GLP-1 pricing from a named pharmacy
Access
Tirzepatide $259 vs semaglutide $179: +$80 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutide + glycine/B12Compounded tirzepatide + glycine/B12
Visit
QuizAsync
Check availability
Magnolia Regenerative MedicineCheap, pharmacy unnamed
A low-cost GLP-1 bought alongside a deep, cheap peptide and hormone menu
Access
Tirzepatide $179 vs semaglutide $99: +$80 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Idgie HealthPharmacy named, plans shown
One menu covering GLP-1, NAD⁺, sermorelin and hair care with the pharmacy named
Access
Tirzepatide $229 vs semaglutide $149: +$80 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
He & She MDFlat dosing, prepay headline
Flat per-dose GLP-1 pricing across injectable and oral, if you read the ladder before the banner
Access
Tirzepatide $339 vs semaglutide $249: +$90 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Prime Doctor RXBoth prices on the card
Readers who want the month-to-month price printed beside the prepay price
Access
Tirzepatide $339 vs semaglutide $249: +$90 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
the edit.Fully disclosed care chain
Buyers who want the practice, pharmacy and management company all named before they pay
Access
Tirzepatide $309 vs semaglutide $209: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
PeptiPriced at every dose
Buyers who want compounded semaglutide or tirzepatide with a price published at every dose
Access
Tirzepatide $199 vs semaglutide $99: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Pallas HealthFlat dose pricing, named pharmacies
Buyers who want one flat price at every dose, or a route to brand-name Wegovy, Ozempic, Zepbound or Mounjaro
Access
Tirzepatide $299 vs semaglutide $199: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatideBrand Wegovy / Ozempic / Zepbound / Mounjaro
Visit
QuizAsync
Check availability
AHBARxHonest prepay arithmetic
A straightforward monthly GLP-1 price with the prepay math shown honestly beside it
Access
Tirzepatide $349 vs semaglutide $249: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
Andrew MedsPrepay ladder, fully shown
Anyone who wants the prepay ladder and its true monthly cost published on one page
Access
Tirzepatide $299 vs semaglutide $199: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsyncVideo
Check availability
Oria MedsPharmacy named with address
A simple two-product menu where both the prescriber network and the pharmacy are named
Access
Tirzepatide $249 vs semaglutide $149: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
Visit
QuizAsync
Check availability
SexyMDHeadline is the 48-week rate
Readers who will commit to a long plan and want the whole ladder published before they do
Access
Tirzepatide $369 vs semaglutide $269: +$100 a month to switch
Insurance
Cash-pay
Medications
Compounded semaglutideCompounded tirzepatide
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Rx.comWeight loss only, well documented
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Tirzepatide $285 vs semaglutide $175: +$110 a month to switch
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Breeze MedsNames its pharmacy
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Tirzepatide $399 vs semaglutide $199: +$200 a month to switch
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SemaglutideTirzepatideOral
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We never show a fabricated price or rating. Facts are shown only where a provider publishes them.

Wegovy or Zepbound: what the trial and the price lists say

SURMOUNT-5 is the one trial that randomized people with obesity to Zepbound or Wegovy. At 72 weeks, average weight loss was 20.2% on tirzepatide and 13.7% on semaglutide. Earlier trials of each drug against placebo (STEP 1 for Wegovy, SURMOUNT-1 for Zepbound) pointed the same way. Our Zepbound vs Wegovy evidence review covers side effects and who stopped treatment.

On price, the two manufacturers sell to self-pay patients in different ways. Novo Nordisk’s self-pay Wegovy pen is $349 a month at standard doses (after two months at a lower rate) and $399 for the 7.2 mg pen. Lilly’s Zepbound vials are priced by dose: $299 at 2.5 mg, rising to $449 at 7.5 mg and above, per 4 weeks. So the approved alternative can cost less than Wegovy at the start of treatment and more at the top of the ladder. Sources and dates are in the GLP-1 cost estimator.

The compounded routes, and what the price gap tells you

Telehealth services also sell compounded semaglutide (Wegovy’s molecule) and compounded tirzepatide (Zepbound’s). Neither is FDA-approved, neither is equivalent to the brand, and the trial figures above were measured on the approved drugs. Their appeal is a lower cash price at higher doses, often flat at every dose.

The gap column is the useful number if you are deciding whether to switch molecules rather than services. A small or zero gap means the same service will move you to tirzepatide for little or no extra cost; a gap of $100 or more means the switch is a budget decision as well as a clinical one. The prices themselves, sorted, are on the cheapest tirzepatide and cheapest semaglutide lists. A third option for some readers is staying on Wegovy through insurance: plans that cover anti-obesity drugs, with the manufacturer’s savings offer, can bring it down to a copay.

How we judge providers

Pricing transparency — is the all-in monthly cost clear, or does a low headline hide consults, labs, and medication fees?
Clinical oversight — real clinician review and dose titration, not a rubber-stamp questionnaire.
Branded vs compounded clarity — does the provider tell you plainly which you’re getting? (It matters — see our compounded-vs-branded explainer.)
Honest insurance handling — straight answers about what is and isn’t covered.

We never show a fabricated price or rating, and access notes appear only where a provider publishes them. Pricing and availability change often — confirm current details on the provider’s own site.

Keep comparing

Weighing the brands themselves? Read how to get Zepbound and the Wegovy cost breakdown. Want a pill instead of an injection? See Ozempic alternatives, which covers the oral routes. Every service with tirzepatide, priced or not, is on the compounded tirzepatide providers page, and the full roster is in the GLP-1 provider roundup.

Choosing between two services? Every provider head-to-head is on one page, including Found vs PlushCare, Hims vs PlushCare and Strut Health vs FORM Health.

Common questions

Is Zepbound better than Wegovy for weight loss?: In SURMOUNT-5, the head-to-head trial, people on Zepbound lost 20.2% of body weight on average at 72 weeks against 13.7% on Wegovy. Tolerability, cost and coverage decide which is right for a given person.
Is Zepbound cheaper than Wegovy without insurance?: At the 2.5 mg starting dose, Lilly's self-pay vial costs less than the standard Wegovy self-pay pen; at 7.5 mg and above it costs more. The short answer at the top of the page has the current figures.
How much more is compounded tirzepatide than compounded semaglutide?: It varies by service. The table shows the difference for every service that publishes both month-to-month prices, from no difference to well over $100 a month.
Can I go from Wegovy to tirzepatide directly?: A prescriber can switch you, but the doses do not convert: Wegovy runs from 0.25 mg to 2.4 mg and tirzepatide from 2.5 mg to 15 mg, so the new drug gets its own starting dose and titration.